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The Carlat Psychiatry Podcast

ProLivRx: How it Works

The Carlat Psychiatry Podcast

Pocket Psychiatry: A Carlat Podcast

Health & Fitness, Alternative Health, Medicine, Mental Health

4.7524 Ratings

🗓️ 26 January 2026

⏱️ 13 minutes

🧾️ Download transcript

Summary

How a new FDA approved device for difficult-to-treat depression engages the brain through the sensory nerves in part II of our interview with Linda Carpenter.

CME: Take the CME Post-Test for this Episode

Published On: 01/26/2026

Duration: 12 minutes, 33 seconds

Chris Aiken, MD and Kellie Newsome, PMHNP have disclosed no relevant financial or other interests in any commercial companies pertaining to this educational activity.

Transcript

Click on a timestamp to play from that location

0:00.0

sensory deprivation. It sounds peaceful, relaxing at first, but it can get pretty depressing when

0:07.8

there's no input heading into the brain. And today, we'll find out what that means for the new

0:13.2

FDA-approved ProLiv RX.

0:26.4

Welcome to the Carlet Psychiatry podcast, keeping psychiatry honest since 2003.

0:30.2

I'm Chris Agen, the editor-in-chief of the Carlat Psychiatry Report.

0:35.1

And I'm Kelly Newsom, a psychiatric MP and a dedicated reader of every issue.

0:48.4

That's the sound of a pottery wheel, and it's just a taste of what you'd be feeling if your hands were coaxing the cool, soft clay as it spins in front of you.

0:53.3

But this study from 2017 will give us a better sense.

0:57.5

It took place in Hong Kong. Researchers randomized 106 patients with depression to a course in clay art,

1:05.6

pottery making, or a similar course in visual art. After three weeks, those who worked the clay with their hands saw improvements in depression.

1:15.0

The visual art group, not so much.

1:17.8

So what made the difference?

1:20.0

One possibility is the senses.

1:22.6

Think about touch.

1:24.4

Maybe you recall a story from your training about the harrowing way that doctor and nurses

1:29.2

discovered the power of touch. It was during World War II. Infants who had lost their parents

1:35.1

in the war were placed in orphanages. This was the antibiotic era, so the first thing on people's

1:40.4

minds was cleanliness, how to keep these babies free of infections. The goal was

1:45.1

achieved, but it came at a cost. Deprived of touch, the children failed to thrive. They regressed

1:50.7

in their development, withdrew, as if depressed. In what psychoanalyst Renee Spitz called

1:56.7

an anachlytic depression. We learned a lesson, and that's why we got out of our way to keep

2:02.4

babies stimulated a day, with touch and even massage. We decorate their rooms with spinning objects

...

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