4.8 • 1.2K Ratings
🗓️ 6 July 2023
⏱️ 19 minutes
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Learn new strategies and tactics to slow the greying of hair and prevent hair loss as you age.
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References:
Fernandez‐Flores, A., Saeb‐Lima, M. & Cassarino, D. S. Histopathology of aging of the hair follicle. J. Cutan. Pathol. 46, 508–519 (2019).
Papaccio, F., D′Arino, A., Caputo, S. & Bellei, B. Focus on the Contribution of Oxidative Stress in Skin Aging. Antioxidants 11, 1121 (2022).
Williams, R., Pawlus, A. D. & Thornton, M. J. Getting under the skin of hair aging: the impact of the hair follicle environment. Exp. Dermatol. 29, 588–597 (2020).
Show Notes:
01:00 We may slow hair graying and hair loss by decreasing chronic inflammation.
02:00 By age 50, 50% of us will have 50% of our hair gray.
02:00 Over 1 year you lose .25% of your hair follicles.
03:00 post-menopausal women have a dramatic increase in follicle loss.
03:30 Oxidative stress can influence gray hair.
04:20 UV stress can affect the hair bulb.
04:40 There is a correlation between graying of hair, facial wrinkling, and crown top baldness and myocardial infarction in men.
08:00 With age, hairs are reduced in diameter and experience follicle miniaturization.
08:55 Chronic inflammation increases damage to DNA proteins and lipids within the hair follicle environment.
10:05 Collagen may be effective in preventing premature wrinkling of the skin and hair loss.
10:55 Bone mineral density correlates with hair loss and hair graying.
11:20 Slowing senescence and purging senescent cells happen with fasting and exercise.
12:25 Minimize exposure to pollution. Avoid excessive sun exposure. Avoid nutrition deficiencies.
13:30 Insulin resistance and PCOS can exacerbate hair loss.
14:00 Sometimes graying from environmental factors may be reversed.
14:30 52% of post-menopausal women experience hair loss.
14:40 Micronized progesterone can help women preserve the integrity of skin and hair follicle.
15:20 Lack of estrogen accelerates changes in hair follicle and skin aging.
17:45 Some shampoos can accelerate graying and hair loss.
18:35 Men with high levels of DHT, consider a ketoconazole shampoo.
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0:00.0 | In today's show, we're going to take a deeper dive into preventing premature |
0:02.7 | grain and hair loss, drawing upon some recently published scientific articles |
0:06.3 | that talk about the histopathology or premature grain hair and also hair loss. |
0:11.0 | We're going to talk about senile alopecia, which is age-associated hair loss |
0:15.3 | and premature grain. |
0:16.8 | Why does this happen? |
0:18.0 | And what can you do about it most importantly, specifically for both men and |
0:22.3 | women, talk about the differences hormonally. |
0:24.8 | For men, there's obviously a concern with dihydrotestosterone DHT, |
0:29.0 | how it impacts the hair bulb and the follicle causing male pattern baldness, |
0:32.9 | but that's not the only factor. |
0:34.9 | It turns out that inflammation, accelerated biologic aging, |
0:38.3 | cellular senescence are all links to premature skin and hair, |
0:43.0 | grain and hair loss. |
0:44.4 | And so it's important that we understand the mechanisms here. |
0:46.7 | We're going to talk about some histology, some science and talk about tactics |
0:51.0 | and what to do because I don't know about you, but you know, |
0:54.0 | when you start to notice your hair thinning, it can be a little depressing. |
0:56.8 | That's just a marker that maybe you're aging and that doesn't make you feel good |
1:01.8 | and grain of the hair and specifically hair loss. |
1:04.6 | It's really hard on one's mindset. |
1:06.6 | And so there's a lot of good evidence to suggest that we can augment this. |
... |
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