4.8 • 688 Ratings
🗓️ 10 June 2025
⏱️ 60 minutes
🧾️ Download transcript
In this episode, Dr. David Jockers and Dr. David Perlmutter explore the root causes of Alzheimer’s and cognitive decline, focusing on metabolic dysfunction rather than amyloid plaques. Dr. Perlmutter explains how insulin resistance and metabolic disturbances contribute to neurodegeneration.
They dive into the role of elevated uric acid in brain health and its connection to dementia and Alzheimer’s risk. Dr. Perlmutter shares actionable steps to manage uric acid levels and improve cognitive function through diet and lifestyle changes.
Learn how to support brain health by balancing blood sugar, nourishing gut bacteria, and incorporating healthy fats. Dr. Perlmutter offers insights on the foods and habits that protect your brain from decline.
In This Episode:
00:00 Understanding Uric Acid and Its Impact
03:12 Interview with Dr. David Perlmutter
05:00 The Rise of Alzheimer's Disease
06:08 Challenges in Alzheimer's Treatment
07:36 Metabolic Factors in Alzheimer's
11:44 Lifestyle Choices to Prevent Alzheimer's
16:42 Key Lab Markers for Cognitive Health
24:55 The Role of Uric Acid in Metabolic Diseases
32:10 Understanding Digestive Issues: The Role of Stomach Acid
34:04 Uric Acid and Its Impact on Health
34:59 Fructose, Diet, and Metabolic Health
41:31 The Role of Nitric Oxide in Health
44:53 Dietary Recommendations for Cognitive Health
54:47 Daily Routine and Lifestyle Tips
58:32 Final Thoughts and Empowerment
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"Alzheimer’s is not a disease of beta amyloid; it’s about brain metabolism and glucose utilization."
~ Dr. Jockers
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Resources:
Get 15% off Paleovalley Beef Tallow: paleovalley.com/jockers – Use code JOCKERS
Save 20% on Just Thrive Digestive Bitters: justthrivehealth.com – Use code JOCKERS
Connect with Dr. David Perlmutter:
Website: https://drperlmutter.com/
Connect with Dr. Jockers:
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Facebook – https://www.facebook.com/DrDavidJockers
YouTube – https://www.youtube.com/user/djockers
Website – https://drjockers.com/
If you are interested in being a guest on the show, we would love to hear from you! Please contact us here! - https://drjockers.com/join-us-dr-jockers-functional-nutrition-podcast/
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0:00.0 | But these days, we are triggering this uric acid accumulation left, right, and center. |
0:06.4 | And as you learn and I learned, to lower uric acid, we have to put people on a low purine diet, |
0:12.3 | remember those, that education. |
0:14.0 | And that would mean lower levels of, you know, lots of meat and high puring foods like yeast and shellfish and small fish, etc. |
0:22.5 | And that's still a messaging on many of the large, well-renowned clinics' websites |
0:27.7 | that you go on a low-peering diet. |
0:29.7 | That's not the elephant in the room. |
0:32.8 | The elephant in the room, what really raises uric acid is a sugar called fructose. |
0:40.2 | Hello and welcome to the Dr. Jockers functional nutrition podcast, the show designed to give you |
0:46.5 | science-based solutions to improve your health and life. I'm Dr. David Jockers, Doctor of Natural |
0:52.9 | Medicine, and creator of Dr.jockers.com, and I'm the host of this podcast. |
0:58.9 | I'm here to tell you that your body was created to heal itself, and on this show, we focus on strategies you can apply today to heal and function at your best. |
1:09.1 | Thanks for spending time with me, and let's go into the show. |
1:15.2 | Well, if you've been listening to this podcast for any length of time, you know you cannot |
1:19.1 | cook or use seed oils. These things are so toxic. They're in so many different things. |
1:24.6 | I'm talking about canola oil, corn oil, soybean, safflower, cotton seed oil. |
1:28.5 | One of the best things you can do for your health is throw out the vegetable oils or the seed oils. |
1:33.7 | But what are good cooking oils? |
1:36.0 | Well, you can certainly use things like olive oil, coconut oil. |
1:38.7 | But one of my absolute favorite cooking oils for its flavor and its health benefits is beef tallow. In particular, |
1:45.2 | 100% grass-fed and finished beef tallow. And that's why I love paleo-vallies, new 100% grass-fed |
1:53.0 | and finished beef tallow. It's loaded with conjugate linoleic acid, which studies show has a variety |
... |
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