PODCAST Ep26 - Dr Paul Mason on Advanced Cholesterol Tests and Much Much More!
The Fat Emperor Podcast
ivor cummins
4.8 • 766 Ratings
🗓️ 8 June 2019
⏱️ 73 minutes
🧾️ Download transcript
Summary
PODCAST Ep26 - Full version of conversation with super well-researched Australian doctor Paul Mason @DrPaulMason - recorded in Boulder, Colorado.
We covered: LDL-P, ApoB, Lipoprotein(a) / Lp(a), Oxidized LDL, Omega 6 Seed Oils, Gilbert's Syndrome, Antioxidants, Bilirubin, Glutathione, Carnitine versus Carnosine, Wheat Germ Agglutanin, GGT, CIMT, CAC, Glycation, Lectins, FODMAP, Magnesium, Selenium, CGM Continuous Glucose Monitors, Parkinson's Disease, and more!
YOUTUBE VIDEO PODCAST HERE: https://youtu.be/pKtRa3JG-Gg
TRANSCRIPT: https://thefatemperor.com/wp-content/uploads/2019/06/Dr.-Paul-Mason-Advanced-Cholesterol-Chat-and-Much-Much-More.pdf
INDEX:
00:00:23 Some insights on the new cholesterol risk factor – Lipoprotein(a) or Lp(a)
00:05:10 Discussion of the role which Oxidised LDL or oxLDL has in heart disease
00:08:32 Glycation damage to LDL – a crucial part of the heart disease problem?
00:09:52 Omega 6 vegetable or seed oils add to the inflammatory cascade of destruction
00:11:17 Oxidized LDL receptors and their place in the system
00:12:33 Gilbert’s Syndrome, Bilirubin and greatly reduced heart attack rates
00:14:50 Glycation, Antioxidants – Carnitine and Carnosine Distinction
00:18:27 The body’s master antioxidant – Glutathione – and the Importance of GGT
00:22:08 Medical school training in nutrition – sadly lacking for doctors?
00:24:23 LDL-P, ApoB100, LDL Receptor activity – the bottom lines
00:29:24 Coronary Artery Calcification (CAC) versus Intimal Media Thickness (CIMT)
00:36:08 HbA1c and Fructosamine as risk factors 00:39:26 Continuous Glucose Monitors (CGM) and blood glucose fluctuations
00:42:05 Insulin measurements, HOMA IR and post-prandial spikes
00:45:58 CGM and problematic medications – rather fix root cause?
00:50:16 Let’s look at Lectins – the taxing toxins from plant world foods
00:56:21 Parkinson’s Disease and the Lectin Connection
00:59:46 Dr. Steven Gundry, poisonous beans, more lectins and the toxic ricin
01:04:27 FODMAP foods, GMO fun, WGA from wheats, lots of bad actors
01:08:07 Nuts! (and Magnesium, Selenium etc.)
01:11:20 Moving forward and emphasizing the core – Pareto-style
Transcript
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| 0:00.0 | have to agree but I would probably extend something a little bit further so rather than |
| 0:04.9 | talking about antioxidant we'll talk about anti-glication and there is a substance I |
| 0:09.4 | don't know if you have heard a carnesine now that's carnesine with a nest not |
| 0:13.0 | carnitine everybody confuses the two that's actually been shown to be a glycation |
| 0:18.0 | inhibitor and it can actually reverse glycation as well. |
| 0:29.0 | Welcome to the Fat Emperor podcast. I'm your host, Ivor Cummins. We're supported by the Irish Heart Disease Awareness charity, which advocates a simple CT scan to reveal your CAC score. |
| 0:35.4 | So know your score and take action to prevent that premature heart |
| 0:39.2 | attack. Everything you need to know will be right here. Dr. Paul Mason, finally get to catch |
| 0:46.9 | up with you all the way from Australia. Pleasure is all mine. Excellent, yeah. I've been watching |
| 0:51.5 | some of your videos and they're superb because you are going through all of the detail of the lipoproteins. |
| 0:57.8 | But you've also got the clinical experience with patients, many, many patients where you're getting to see this in real life play out. |
| 1:04.3 | So maybe today we'll talk a little bit around these LDLP and LP little A and some of these advanced lipoproteins and what they really mean. |
| 1:12.1 | One of my favourite topics. |
| 1:14.1 | Right. |
| 1:15.1 | So where do we start then? |
| 1:16.6 | Well I guess LP little A is one that's becoming very popular out there in the press. |
| 1:21.1 | And a few years ago you'd hardly hear about it. |
| 1:23.6 | Now I've done quite a bit of research in LP little A, but I think you've gone that step further. |
| 1:28.5 | So maybe the context around LP little A, when it's bad when it's high, when it may not be bad when it's high, kind of what it's all about for someone who gets a high LP little A reading. |
| 1:39.9 | Well, I guess my first thought on LP little A is that it's just a surrogate marker. |
| 1:45.4 | And I guess what I mean by a surrogate marker is that it's there, |
| 1:49.2 | but it's there by association, not by causation. |
... |
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