We imagine physics is objective. But quantum physics found the act of human observation changes the outcome of experiment. Many scientists assume this central role of the observer is limited to just quantum physics. But is this an error? As Heisenberg puts it, "what we observe is not nature in itself but nature exposed to our method of questioning." In all our studies of reality and nature then, the observer plays a role -- not just in quantum physics. Should we recognize science can never access reality independent of the observer? Should we re-define science not as uncovering objective reality, but as uncovering the functions, limitations and structures of the mind of the observer themselves? And if we cannot remove the observer, might quantum physics help us to understand the observer - as Roger Penrose suggests consciousness "reeks of something quantum mechanical." Sabine Hossenfelder is a research fellow at the Frankfurt Institute for Advanced Studies, author of Lost in Math: How Beauty Leads Physics Astray and regular contributor to Forbes. She is known for her popular YouTube channel Science Without The Gobbledygook Eric Weinstein is an American podcast host, managing director of Thiel Capital, doctor of mathematical physics and member of the "intellectual dark web". Carlo Rovelli is an Italian theoretical physicist who works mainly in the field of Quantum Gravity. Carlo's popular science book Seven Briefs Lessons on Physics has been translated into 41 languages and sold over one million copies. In 2019 he was named one of the 100 most influential thinkers by Foreign Policy magazine. Brian Keating is a groundbreaking American cosmologist who works on observations of the cosmic microwave background, leading the BICEP, POLARBEAR2 and Simons Array experiments. To join Brian's mailing list: https://briankeating.com/mailing_list.php The Institute of Art and Ideas features videos and articles from cutting edge thinkers discussing the ideas that are shaping the world, from metaphysics to string theory, technology to democracy, aesthetics to genetics. Subscribe today! For debates and talks: https://iai.tv For articles: https://iai.tv/articles For courses: https://iai.tv/iai-academy/courses Be my friend: 🏄‍♂️ Twitter: https://twitter.com/DrBrianKeating 🔔 Subscribe https://www.youtube.com/DrBrianKeating?sub_confirmation=1 📝 Join my mailing list; just click here http://briankeating.com/mailing_list.php ✍️ Detailed Blog posts here: https://briankeating.com/blog.php 🎙️ Listen on audio-only platforms: https://briankeating.com/podcast.php Join Shortform through my link Shortform.com/impossible and you’ll receive 5 days of unlimited access and an additional 20% discounted annual subscription! Can you do me a favor? Please leave a rating and review of my Podcast! On Apple devices, click here, scroll down to the ratings and leave a 5 star rating and review The INTO THE IMPOSSIBLE Podcast https://apple.co/39UaHlB On Spotify it’s here on @audible_com it’s here and other ways to rate here: https://briankeating.com/podcast Please join my mailing list; click here https://briankeating.com/list for your chance to win real space dust!! A production of http://imagination.ucsd.edu/ Support the podcast: https://www.patreon.com/drbriankeating A production of http://imagination.ucsd.edu/ Producer Stuart Volkow P.G.A. Support the podcast: https://www.patreon.com/drbriankeating Learn more about your ad choices. Visit megaphone.fm/adchoices