Hey everybody and welcome to the eighth episode of the Physician

Assistant Boards dot-com podcast today I want to be going over Cushing's

Disease. It's ideology, presentation, diagnosis, and treatment.

But before we get started, I just want to let you guys know that I have the Cardiology and

pulmonary section completed over on the website.

I will also be done with the Musculoskeletal slash rheumatology section by the end of this weekend as well.

The next section that I'll be tackling for you guys is the reproductive system.

So I'll be adding each disease process from the Pants Blueprint on the

Physician Assistimports.com website every day. So please feel free to check

that out. All right, so let's get started with Cushing's disease or syndrome.

The first thing you need to know is the difference.

So we have Cushing's Disease and we also have Cushing's Syndrome.

Now they both have an elevated cortisol level. The difference here is that disease

will be derived from the pituitary. And syndrome simply means any elevated cortisol level

from an ectopic source. So you need to differentiate the two

because treatment will vary considerably. Another way to look at this is also that cortisol level might be independent of a c.

Or dependent on a c.

So to quickly review, Cushing's disease equals pituitary problem. Cushing's syndrome means other possibilities of elevated

cortisol levels.

A really quick side note for you guys.

So the Hypothelamus will secrete corticotropin releasing

hormone, also called CRH. This is going to send a signal down to the pituitary to release A.C.T.H.

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