On Vaccines and Vaccinology, in COVID and Beyond

The a16z Show

a16z

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4.2 • 1.2K Ratings

🗓️ 14 August 2020

⏱️ 57 minutes

🔗️ Recording | iTunes | RSS

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Summary

with @rvenkayya @jorgecondebio WHEN are we going to have a COVID-19 vaccine, and how the heck are we going from 12 years of vaccine development compressed into 12 months or so? What will and won’t be compromised here, and where do new technologies (like mRNA) come in? Where will vaccines likely be distributed first; who will and won't get them initially; how do we maintain not just safety and efficacy of vaccines but trust and transparency when it comes to mis/information? We may actually see the emergence of a "Neo Anti-Vaxxer"... but we may also be entering a renaissance for vaccinology after this pandemic.

Transcript

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0:00.0	Hi everyone welcome to the A6 and Z podcast I'm Sonel and today's episode is all about vaccines
0:06.7	when exactly will we get one for COVID-19 how where and why and while it's a super timely question and concern, this episode
0:15.1	covers a wide range of topics all about vaccines and vaccinology well beyond the
0:19.6	current pandemic. Beginning with the quick primer on vaccine development to what will have to give up to shrink development
0:26.2	from a typical 12 years or so to 12 months or so, what modern technologies are being applied
0:31.1	to this current development, some for the very first time, including
0:34.5	MRNA vaccines, where manufacturing and scale up comes in, and by the way, why have we traditionally
0:40.2	used eggs and growing vaccines?
0:42.2	The conversation also touches on business
0:44.0	models, opportunities for all kinds of different players and tough public
0:48.1	policy questions around public transparency who gets the vaccines first when they arrive and inequalities, possible impacts on different
0:55.9	populations, risks, and much more.
0:58.1	How does a question of vaccines impact school reopening?
1:01.1	Where does misinformation come in? These are both topics by the way
1:03.9	that we're diving deep on in upcoming episodes and will we see the emergence of a
1:08.4	different kind of anti-Vaxer movement here? A6- General Partner, Jorge Conde interviews Rajiv
1:14.2	Van Kaya, president of the Global Vaccine Business Unit at Decata Pharmaceutical
1:18.6	Company, where he leads vaccine development for Dengue
1:21.4	Narovirus and Zika and is co-leading their response to the COVID-19 outbreak.
1:25.9	Venkaya also formerly served in the White House as special assistant to the
1:30.2	president for bio-defense, where among things, he was a principal author of the National
1:35.3	Strategy for Pandemic Influenza Plan. So they cover a lot of ground on this episode.
	...

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