5 • 716 Ratings
🗓️ 24 September 2020
⏱️ 15 minutes
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0:00.0 | Hey all, welcome back to the Real Life Pharmacology podcast. I'm your host, pharmacist Eric Christensen. |
0:06.0 | Thank you so much for listening today. As always, go to real life pharmacology.com, |
0:12.5 | snag your free top 200 study guide. It's a 31 page PDF. It costs you nothing but an email. |
0:20.2 | And we'll get you updates on when we have a new blog |
0:23.6 | posts and or other education coming out. So definitely go take advantage of that resource at |
0:30.5 | real life pharmacology.com. All right. So getting in to the drug for the day, we've got omeprosol. |
0:40.2 | Brand name of this medication is Prilosec. |
0:43.4 | Definitely, I can tell you from clinical practice experience, very heavily used drug, and certainly ranks high on the list of the top 200 drugs. |
0:56.3 | This drug is classified as a proton pump inhibitor, also well known as abbreviated PPI. |
1:05.3 | This drug blocks parietal cells in the stomach. |
1:10.7 | And these parietal cells release hydrogen ions, |
1:13.9 | which causes an acidic environment. |
1:17.9 | That acidic environment can certainly lead to symptoms of heartburn, |
1:24.2 | potential for GI ulceration, and things of that nature. |
1:28.3 | So again, that hydrogen-potassium ATP pump is what's inhibited, and that ultimately |
1:38.3 | blocks the pumping of hydrogen ions or protons into the stomach, which raises the pH of the stomach, |
1:48.2 | and potentially suppresses that acid, which may be causing that pain or irritation in patients |
1:56.9 | that have excessive production. So with that said, what are we going to treat? What |
2:02.5 | are we going to manage? Obviously things like heartburn, gastroesophageal reflux disease or GERD, |
2:10.6 | peptic ulcer disease, Barrett's esophagus, and honestly in clinical practice, I definitely see it as a catch-all if a patient is experiencing |
2:23.4 | stomach-type symptoms and they're trying to figure out what's going on. You'll often see these started to help reduce symptoms now that may be right or wrong in certain situations, but |
2:36.6 | definitely have seen it thrown on board quite a bit for various indications. One other one |
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