Nature Podcast: 24 March 2016
Nature Podcast
podcast@nature.com
4.5 • 893 Ratings
🗓️ 23 March 2016
⏱️ 31 minutes
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| 0:00.0 | This week, the brain cells that make some rats thrill-seekers and others overcautious. |
| 0:07.8 | We could instantaneously convert them from risk-seeking to risk-averse. |
| 0:12.6 | And how to go from make-use dispose to make-use repair reuse. |
| 0:18.3 | Whatever I have, I try to figure out how long I can use it. And that's why I've |
| 0:24.5 | kept my first car from 1969, and I'm still driving it. Plus using magnets and radio waves to control |
| 0:31.6 | the activity of an animal's cells. In some of the studies we published earlier, we could just change the activity of a gene by literally |
| 0:40.1 | waving a magnet that was bought at a hardware store over the liver of an animal. |
| 0:44.4 | This is the nature podcast for March the 24th, 2016. |
| 0:48.6 | I'm Adam Levy. |
| 0:49.6 | And I'm Kerry Smith. |
| 0:53.8 | Scientists have known for a long time that changing the electrical activity of brain cells |
| 0:58.6 | affects their function. That's why electroshock therapy is still used to treat a range |
| 1:03.2 | of psychiatric disorders. But over the years we've got better and better at controlling |
| 1:08.2 | the electrical activity of specific regions of the brain. |
| 1:12.1 | To treat diseases like Parkinson's, for example, an electrode can be implanted to stimulate neurons |
| 1:17.8 | in a part of the brain. But the problem with methods like these is that they require permanent |
| 1:22.9 | implant in the brain, which is very invasive. Wouldn't it be great if you could just turn cells on and off with just a radio wave or a magnet? |
| 1:32.2 | Well, Jeffrey Friedman and collaborators at Rockefeller University in New York definitely thought so. |
| 1:37.7 | I called Jeffrey up to find out about their new approach. |
| 1:41.2 | So we've developed a method that allows you to control the activity of nerve cells |
| 1:47.4 | and other cells now using a magnetic field. The system takes advantage of two different components. |
| 1:54.3 | The first component is a channel known as TriPV1. TriPV1 is a receptor in your tongue and also nerve cells that |
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