Naringin — A Citrus Flavonoid That Reduces Heart Disease Risk
Dr. Joseph Mercola - Take Control of Your Health
Briana Mercola
4.6 • 1.6K Ratings
🗓️ 24 September 2025
⏱️ 8 minutes
🧾️ Download transcript
Summary
- Cardiovascular disease kills nearly 18 million people worldwide each year, but natural compounds like naringin in citrus fruits are showing strong protection for arteries and heart health
- Naringin blocks ferroptosis, a deadly form of heart cell death during heart attacks, while silencing inflammation alarms to protect cardiac muscle under stress
- Human trials show naringin improves cholesterol profiles, reduces arterial stiffness, and enhances overall cardiometabolic health within just 90 days of consistent intake from citrus sources
- Beyond the heart, citrus flavonoids improve insulin sensitivity, lower harmful cholesterol, reduce belly fat, and stabilize blood sugar, offering metabolic benefits against obesity and diabetes
- Naringin also protects the liver from drug-induced damage and slows tumor growth in cancers like breast, lung, and colon by restoring cell self-destruction and cutting tumor blood supply
Transcript
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| 0:00.0 | If a simple citrus compound could lower your heart disease risk, steady your metabolism, |
| 0:05.0 | and protect your liver, would you make room for it this week? |
| 0:08.0 | Welcome to Dr. Mercola's cellular wisdom. |
| 0:12.0 | Stay informed with quick, easy-to-listen summaries of our latest articles, perfect for when you're on the go. |
| 0:17.0 | No reading required. Subscribe for free at Mercola.com for the latest health insights. |
| 0:22.4 | Hello, and welcome to Dr. Mercola's cellular wisdom. I'm Ethan Foster, and today we're |
| 0:28.1 | looking at Naringen, the citrus bioflavinoid linked to better endothelial function, calmer inflammation, |
| 0:34.6 | and measurable gains in cardiometabolic health. I'm Ethan, and I'll guide us through |
| 0:39.6 | what the research shows and how you can apply it without guesswork. I'm Alara Skye. Naringen is a |
| 0:45.3 | flavon glycoside most abundant in grapefruit, pommelow, and some mandarin's. It gives certain |
| 0:51.0 | citrus that distinct bitter note, but more importantly, your gut microbes |
| 0:55.4 | convert it into Narangenin, the active form that your body actually uses. |
| 1:01.3 | Not all citrus is high in Naringen, grapefruit and pomelo lead, while lime contains less. |
| 1:07.8 | You'll find it in the peel, pith, seeds, and juice. |
| 1:11.6 | Cardiovascular disease now claims nearly 18 million lives a year. |
| 1:16.6 | And Naringen is drawing attention for how it addresses the core drivers, oxidative stress, |
| 1:21.6 | stiff vessels, and chronic inflammation. |
| 1:24.6 | A recent systematic review spanning 2000 through mid-2025 analyzed 62 studies, |
| 1:31.6 | human, animal, and cellular, and centered on endothelial function and inflammatory markers. |
| 1:38.1 | The theme was consistent. Norengen engages multiple pathways that matter for arterial flexibility |
| 1:43.6 | and cardiac resilience. |
| 1:46.0 | Human data stand out. |
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