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Modern Wisdom

Mostly Wise: Matt McCusker, Andrew Huberman & Tom Segura - #1102

Modern Wisdom

Chris Williamson

Health & Fitness, Society & Culture

4.65.9K Ratings

🗓️ 25 May 2026

⏱️ 162 minutes

🧾️ Download transcript

Summary

I spent a really long time putting this together, I really hope you enjoy it! In this inaugural episode of Mostly Wise, we explore: The non-sexual benefits of tadalafil (Cialis). Why Retardmaxxing might be the most underrated life hack. The strange reasons why people are making AI clones of their exes. Why America is addicted to lawsuits. If Love Island is harder than Navy SEAL selection training. and much more Guests Matt McCusker is a comedian, writer, author, and podcaster Dr Andrew Huberman is a neuroscientist, Associate Professor at the Stanford University School of Medicine and a podcaster. Tom Segura is a comedian, podcaster, and actor. Sponsors: See discounts for all the products I use and recommend: ⁠⁠https://chriswillx.com/deals⁠⁠ Get up to $350 off the Eight Sleep Pod 5 at https://eightsleep.com/modernwisdom Get 35% off your first subscription on the best supplements from Momentous at https://livemomentous.com/modernwisdom Get 160+ lab tests for just $365 and save an extra $25 at https://functionhealth.com/modernwisdom Get 15% off your first order of my favourite Non-Alcoholic Brew at https://athleticbrewing.com/modernwisdom Get ChatGPT to explore ideas, solve problems, and learn faster at ⁠https://chatgpt.com Timestamps: (0:00) Should All Men Be Taking Erectile Dysfunction Medication? (5:24) The GLP-1-Free Way to Get Lean (8:28) Why Comedians Make Great Actors (14:02) What Science Reveals About Comedians (25:33) How Love Island Manipulates Sleep (30:39) Is Retardmaxxing the New Way of Living? (46:28) The Risk of Recreating Your Ex With AI (49:32) Has Surveillance Killed Serial Killers? (52:53) Falling is a Billion-Dollar Industry (57:57) Are NASA Conspiracies Going Too Far? (01:01:05) Are These the Craziest Conspiracy Theories? (01:12:00) The Origins of the Secret Service (01:17:08) Can Cannabis Trigger Psychosis? (01:24:01) Is Nostalgia Ruining the Present? (01:31:10) The Unexpected Benefits of Fap Naps (01:38:38) The Best Method to Optimise Your Sleep (01:45:32) Are Kids Becoming Smarter? (01:57:12) Is Hollywood Exploiting OnlyFans Creators? (01:59:58) Has Chris’ Voice Been Stolen? (02:06:18) Are Clang Associations a Sign of Psychosis? (02:09:57) The Crazy Spending Habits of Johnny Depp (02:15:56) What Happens When You Don’t Sleep? (02:19:19) Are Backyard Ultra Runners the Toughest Athletes? (02:23:04) Can You Get Shredded Sugarmaxxing? (02:25:47) Does the Marshmallow Test Hold Up? (02:31:38) Is Sunscreen Actually Bad For You? (02:40:20) Where to Find the Guys Extra Stuff: Get my free reading list of 100 books to read before you die: ⁠⁠https://chriswillx.com/books⁠⁠ Try my productivity energy drink Neutonic: ⁠⁠https://neutonic.com/modernwisdom⁠⁠ Episodes You Might Enjoy: #577 - David Goggins - This Is How To Master Your Life: ⁠⁠lnkfi.re/SN-Goggins⁠⁠ #712 - Dr Jordan Peterson - How To Destroy Your Negative Beliefs: ⁠⁠lnkfi.re/SN-Peterson⁠⁠ #700 - Dr Andrew Huberman - The Secret Tools To Hack Your Brain: ⁠⁠lnkfi.re/SN-Huberman⁠⁠ - Get In Touch: Instagram: ⁠⁠https://www.instagram.com/chriswillx⁠⁠ Twitter: ⁠⁠https://www.twitter.com/chriswillx⁠⁠ YouTube: ⁠⁠https://www.youtube.com/modernwisdompodcast⁠⁠ Email: ⁠⁠https://chriswillx.com/contact⁠⁠ - Learn more about your ad choices. Visit megaphone.fm/adchoices

Transcript

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0:00.0

I keep seeing tweets about how everyone should be taking erectile dysfunction medication.

0:03.8

Is that true?

0:04.6

Low grade, whatever, yeah, like the low grade donor.

0:06.8

So, todalophyll, which is the generic name for Cialis, was developed first as a prostate

0:13.7

health drug.

0:14.7

And then people took more of it and realized that at higher dosages, it can be effective for

0:19.9

erectile dysfunction.

0:20.7

But low dose is good for prostate health. Low dose, like 2.5 to 5 milligrams per day, is very helpful for perfusion of the prostate. And also, it causes vasodilation in the brain. So things like strokes, I mean, you want blood flow, right? You don't want excessive blood flow, you've got a headache from it. But our chair of male sexual health and urology at Stanford, Mike Eisenberg, he came on the

0:43.0

podcast and he said pretty much every male over 40 or so should be taking about 2.5 to 5 milligrams

0:48.6

per day. Does it still get you pretty hard too? It definitely will improve. Just curious.

0:53.9

It will definitely, it will definitely notch up like erectile strength,

0:59.5

but unlike, you know, some health people out there, I'm not like using the calipers

1:05.7

to measure the strength.

1:07.1

You know, I'd put, you know, I asked someone else to measure.

1:08.9

And, and, and, and, and she tells me that, like, you know, not, you know,'d put i asked someone else to measure and and and and and she tells me that like

1:11.8

you know not you know it's all good i don't you mean yeah just tell her close her hand close her hand if

1:18.0

you can well no i've never actually i've never actually subjected to the grip test um you know i don't

1:24.6

want to tempt anybody um but in all seriousness, you know, the drug, this drug

1:29.1

that was developed for vasodilation, which is now used for erectile dysfunction, it really was developed

1:33.8

first as a prostate health drug. And a lot of sitting, the prostate's weird, too, because it doesn't

1:38.3

get a lot of blood flow compared to other tissues, doesn't have it. Speak for yourself.

1:41.7

Same immune system. Yeah, well. What if you sit with the Well, you know, you're kegling all day. So, you know, we realized, you know, Chris said to pull up to this little piece of tape so we didn't catch him kegling over the desk, you know, cagling, kegling. Isn't it, I kind of feel like it could just be a sigh up to normalize erectile dysfunction medication by dudes that have got erectile dysfunction. By doing that, every man should be taking it that nobody is then on the outside. That's fair. I take the six, it's like five to six milligrams in the morning. You do in the morning. Yeah, every morning. What's a, what's a little troc, what's a little mint? Is that half? What's like a, Oh, I don't know.

...

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