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The Diary Of A CEO with Steven Bartlett

Most Replayed Moment: Mouthwash REVERSES The Benefits Of Exercise! Dr Nathan Bryan

The Diary Of A CEO with Steven Bartlett

FlightStory

Business, Society & Culture, Education

4.517.8K Ratings

🗓️ 3 April 2026

⏱️ 24 minutes

🧾️ Download transcript

Summary

Dr Nathan Bryan is a leading nitric oxide researcher and biochemist, known for his work on cardiovascular health, blood pressure, and human physiology. In this moment, he reveals a surprising and controversial insight: everyday oral health habits like mouthwash and toothpaste may be disrupting your oral microbiome and blocking nitric oxide production. He explains how this directly impacts blood pressure, circulation, and even reverses the benefits of exercise - unpacking the science behind one of the most overlooked systems in human health. Listen to the full episode here: Spotify: https://g2ul0.app.link/JbS4DZVXV1b Apple: https://g2ul0.app.link/3WbhlB1XV1b Watch the Episodes On YouTube: https://www.youtube.com/c/%20TheDiaryOfACEO/videos Nathan Bryan: https://n1o1.com/about-dr-nathan-bryan/?srsltid=AfmBOooOFqsJRAP7whrtk26AsE0bI1-NrNlxbJVP-uhBoHYLuAEPy673

Transcript

Click on a timestamp to play from that location

0:00.0

If I've just listened to everything you've just said there, and I want to improve my oral microbiome, what should I be doing?

0:09.8

Well, I think the most important thing we've learned is what you shouldn't be doing.

0:13.2

Yeah.

0:13.9

So it's not what should we do, it's what we shouldn't be doing.

0:16.6

Number one, we have to get rid of fluoride.

0:19.0

You know, just this past weekend I was speaking at a dental conference in Salt Lake City,

0:22.9

and there were people there from the National Toxicology Program,

0:26.4

which in the U.S. is the organization tasked with,

0:30.1

if there's any kind of risk of exposure of environmental toxicant,

0:34.7

they're charged with doing the toxicology studies to see if there's an

0:38.0

increased risk. What is the risk? And is there a safe level that is without risk? And what they

0:44.2

report is that fluoride, there's no benefit of fluoride, and it's all risk. It lowers IQ in kids

0:50.3

by as much as seven points. And it shuts down your thyroid function. And it's a neurotoxin.

0:57.7

And as I mentioned before, most toothpaste has fluoride in it. And if you read the back of your

1:03.7

toothpaste, it will tell you, at least in the U.S., I don't know about it in other countries,

1:08.3

but it says if you swallow this, call poison control.

1:12.6

Because it's a poison.

1:13.9

They're putting poison in toothpaste.

1:19.2

And then if you also pay attention, it says, only put a pea-size amount of toothpaste on your toothbrush, a pea-size.

1:22.6

But everybody that I know fills the entire bristle of the toothpaste with toothbrush with toothpaste. So that's about 10 or 15,

1:31.4

sometimes 20, pea size amounts of toothpaste. And a pea size amount of toothpaste contains about

1:37.2

half a milligram of fluoride. Now, if you're using 10, 20 times more than that pea size,

...

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