So, guys, Derek, more platesmorenates.com. Today we're going to be talking about micro-needling and PG-E2.

So, Prosting Landon E2 is, if you've seen my other videos on castor oil on PGD2 antagonists, you probably have some idea of what PGEE2 is at this point.

It's essentially the prosthicin that promotes relaxation of tissues as opposed to

prostate gland in D2.

PGD2 is more of the constriction of tissues.

And this is why women, when they're trying to induce labor or people who need a laxative or something like that they'll

have a massive for laxative effect 15 milliliters of castor oil is common for inducing labor it's

upwards of 60 milliliters and then some women just get straight pg.2 so regardless if it's via

castor oil or via straight pg.E2 the outcome is trying to accomplish the

relaxation of tissues which in turn also could potentially relax tissues on the scalp that have

been you know constricted via this you know inflammatory cascade of events after

androgen receptor activation whereby the hair follicle is essentially undergoes what many

theorized to be hypoxia or you know miniaturization whereby the tissues around the

hair follicle essentially constrict and kind of like, you know, prevent it from growing properly.

So this is why the theories around, you know, why PGD2 is elevated in balding scalps and PGE2, there's not enough there and blah, blah, blah.

It's, you know, logically you would conclude, okay, well, PGE2, if I can just use more of it and I can put more PGE2

right on the tissue that needs it, then I can relax that tissue and allow for proper hair

regrowth, which obviously a logical conclusion, which I had to test out, obviously. So the thing

is, is there are protocols whereby people focus on a different

area of the cascade of events that leads to the eventual, you know, like actual balding of the scalp.

So some individuals who get side effects or just don't want to, you know, go down that route,

will avoid five alpha reductase inhibitors will avoid anti androgens will avoid

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