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Hey, everyone, this Dr. Rucho.

Just wanted to give you your fast facts for today's show, which is on the microbiota and obesity.

The best science to date shows there is no consistent relationship between obesity and

the microbiota. High-level data also suggests that the microbiota does not cause obesity

and is more so a reaction to the obesity state. This means microbiota testing has very little value in treating obesity,

at least right now. This is supported by clinical data showing poor results when manipulating

the microbiota in attempts to treat overweight or obesity. In prebiotics, we see the best weight

loss of 2.3 pounds. In probiotics, we see the best weight loss of 2.2 and 3.7 pounds.

With fiber, we see an average weight loss of 4.2 pounds.

And with fecal microbiotal transplant therapy, or FMT, we see no change in weight or body

composition.

Now, you've probably heard things that are different than what I just said.

Most of the confusion about the microbiota, in my opinion, comes from misinterpreting human data.

For example, thinking those in the U.S. should have the same microbiota as those in Africa.

The microbiota that helps Africans may make those in the US consipated in fat.

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