Hey, folks. Welcome to the Dark Horse podcast Inside Rail. This one is going to be fascinating, folks.

I am sitting with Mark Cannon, who is a professor emeritus from Children's Hospital in Chicago and Northwestern University.

He is in some sense a continuation of a little series that we've been doing here with Dr. Jones

and Dr. Clancy, where we've talked a good deal about things that happen at the mucosal

interfaces of the body.

And, well, let's just say there's a lot to talk about here.

But before we do, let me just say, welcome Dr. Cannon.

Thank you so much, Brett, for having me on. I really appreciate this. I feel it's really quite an honor to be on your podcast and to talk to you about something I'm very passionate about.

And people can tell it. Like when I do a

presentation at a meeting, I get very passionate. I'm walking around, excited. I don't want to

stop because there's so much we can share. There's so much information out there. To be honest with you,

what we can talk about today will be obsolete in six months.

Information will be absolutely archaic in a very short period of time because whenever I get like a presentation ready for a meeting, a healthcare meeting, I find myself changing things a day or two before, a week

before, because of new publications. And so I think to set this off, what got me going was

just by chance, I worked with a microbiologist. And this was back in 1974, 74, 75,

a little bit of a time ago, it seems like yesterday. And he was way ahead of his time. He was

looking at pathogenic bacteria and how they had an influence

on the immune system of the body. And we did not understand it. No one did. He had, he was,

I think he is still around, but he is quite a bright individual.

But I got trained. I went through my training and got my degree, went to Children's Hospital

in Chicago, stayed taught. I became like everyone else treating symptoms, not disease, not understanding the basis behind

disease, thinking of everything in one dimension, not even two dimensions. And then I had a

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