Hey, all, welcome back to the Real Life Pharmacology podcast. I'm your host, pharmacist, Eric Christensen,

and I thank you so much for listening today. Go check out Real Life Pharmacology.com. Get your free 31-page

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So go do that, real-life pharmacology.com. All right, let's get into the drug of the day today, and that is

myperidine. Now now this is definitely an older

medication brand name of this medication is demoral it has been around for a long long time

when i first started practice in 2009 i saw this medication a little bit. On a positive note, I can't recall really the last

time I've seen Mapyradine used. It's been quite some time. So that is a good thing because we've

definitely got some warnings and potential adverse effects associated with this medication.

So first and foremost, myperidine is an opioid used in pain management or can potentially be used in pain management.

Just as a reminder, an opioid drug that binds opioid receptors.

And when that binding occurs, that action leads to essentially blocking the pain signals

from going to the central nervous system.

And then obviously that interpretation of your brain saying that hurts,

the opioids and myperidine block that pathway.

So ultimately this reduces perception and response to pain.

Meparidine dosing, it's in the neighborhood of 50 to 150 milligrams.

You know, I.M., subcue, oral, these are all possible options, and can be given IV as well.

One additional indication that you may see a peridine used for, it's kind of a unique one,

but you may see IV utilized in post-operative shivering.

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