5 • 716 Ratings
🗓️ 5 October 2023
⏱️ 12 minutes
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0:00.0 | Hey all, welcome back to the Real Life Pharmacology podcast. I'm your host, pharmacist, Derek Christensen, |
0:05.4 | and I thank you so much for listening today. As always, go check out real-life pharmacology.com. Get your |
0:11.3 | free 31-page PDF on the top 200 drugs. It's a great study guide, no-brainer for those in clinical |
0:18.6 | practice or those going through pharmacology courses. |
0:21.6 | So simply an email, we'll get you access to that. |
0:24.4 | We also get you updates when we've got other new content available as well. |
0:30.3 | All right, let's get into the drug of the day today, and that is moxacam. |
0:36.0 | Brand name of this medication is Mobek. |
0:38.9 | And this is an insed. |
0:40.8 | Just a quick reminder, insed stands for non-steroidal, anti-inflammatory drug. |
0:46.8 | Some of the common ensets, ibuprofen, naproxin, those are over-the-counter, |
0:52.0 | and probably the two most common that I see in practice. |
0:55.4 | But I do occasionally see molyxicam. |
0:58.8 | So with that mechanism of being an N-Sed, this medication inhibits Cox enzymes, |
1:07.5 | and specifically Cox 1 and Cox 2. |
1:11.6 | That ultimately reduces prostaglandin synthesis, |
1:15.6 | which can lead to a reduction in pain and inflammation. |
1:21.6 | Now let's talk specifically about Meloxicam. |
1:24.6 | Meloxicam tends to prefer Cox 2 over Cox 1. |
1:32.3 | Now, as you increase doses, that selectivity tends to go away, |
1:37.3 | and you get Cox 1 and Cox 2 inhibition. |
1:41.3 | But what that means is if we've got a little bit of a preference towards cox two inhibition |
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