MDMA Therapy Without the Drugs? How Vibration Hacks Your Brain for Neuroplasticity | Dave Rabin : 1260
The Human Upgrade with Dave Asprey
Dave Asprey
4.6 • 7.3K Ratings
🗓️ 14 March 2025
⏱️ 61 minutes
🧾️ Download transcript
Summary
What do vibrations and the psychedelic experience have in common?
MDMA therapy is revolutionizing mental health treatment, helping people overcome PTSD, anxiety, and emotional trauma with unprecedented success. But what if you could tap into those same powerful benefits—without taking a single drug?
It turns out your brain responds to more than just chemistry. Vibration, frequency, and rhythm have been shaping human consciousness for millennia—from ancient chanting rituals to modern neuroscience breakthroughs. Could the right vibrations unlock the same neuroplasticity and healing pathways as psychedelics?
In this episode, Dave Asprey sits down with Dr. Dave Rabin, a neuroscientist, psychiatrist, and psychedelic researcher, to explore how vibrations can rewire your brain, enhance neuroplasticity, and even mimic the effects of MDMA therapy. Dr. Rabin’s work led to the creation of Apollo Neuro, a wearable device that taps into your nervous system’s natural ability to regulate stress, boost focus, and accelerate recovery—without pharmaceuticals.
What You’ll Discover in This Episode:
• How specific vibrations trigger deep relaxation and neuroplasticity
• Why MDMA therapy works—and how vibration-based tech can simulate it
• The surprising science behind music, frequency, and altered states
• How Apollo Neuro enhances sleep, focus, and emotional resilience
• The overlooked role of heart rate variability in longevity and health
• Why stress is the biggest obstacle to healing—and how to override it
**Apollo Neuro | To get an Apollo wearable, go to https://apolloneuro.com/Dave and save 15%**
Resources:
• Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/
• Apollo Neuro Instagram: https://www.instagram.com/apolloneuro/?hl=en
• Apollo Neuro Website: https://apolloneuro.com/Dave
• Danger Coffee: https://dangercoffee.com
• Dave Asprey’s Website: https://daveasprey.com
• Dave Asprey’s Linktree: https://linktr.ee/daveasprey
• Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com
• Own an Upgrade Labs: https://ownanupgradelabs.com
• Upgrade Labs: https://upgradelabs.com
• 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com
Timestamps:
00:00 Trailer
00:40 Intro
01:18 Exploring Vibration in Biohacking
02:29 Introduction of Dr. Dave Rabin
02:53 Understanding Vibration and Its Impact
04:47 The Apollo Neuro Device
08:44 Using Apollo for Different States
11:41 Apollo in Psychedelic Therapy
24:32 Clinical Trials and Studies on Apollo
29:32 Heart Rate Variability and Biohacking
33:02 Revolutionizing Sleep with Apollo
34:40 Apollo’s Long-Term Effects and Dependency
37:16 Apollo’s Impact on ADHD and Psychiatric Disorders
45:22 The Importance of Human Connection and Simple Solutions
49:56 Longevity, Healthspan, and Future Innovations
57:23 Final Thoughts and Discount Offer
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Transcript
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| 0:00.0 | MDMA therapy is really unique because it's one of the most well-understood psychedelic therapy techniques, |
| 0:05.5 | and it works by amplifying safety cascades in our emotional brain. It sends positive emotion. And so we |
| 0:11.5 | were trying to use sound waves to replicate some of those safety states in the body. The body has |
| 0:18.0 | ways of regulating itself based on sound. |
| 0:21.6 | It's actually been known for thousands of years that music and singing or chanting, |
| 0:26.6 | the creation of music from the body, can actually induce what's called resonance states, |
| 0:31.6 | meaning states of harmony between the heart and lungs. |
| 0:34.6 | What happens when you have the right vibrations in the right place? |
| 0:40.0 | You're listening to The Human Upgrade with Dave Asprey. |
| 0:46.2 | Today is an upgrade spotlight edition where I bring an innovator, a founder, an inventor in |
| 0:53.3 | to talk about something new and interesting in the world |
| 0:57.1 | of biohacking. And today we've got a returning guest, Dr. Dave Rabin, who's a well-known, |
| 1:04.4 | distinguished figure in neuroscience, psychiatry, and psychedelic medicine, and some of the spiritual sides of it as well. |
| 1:14.0 | We're friends and have gotten to know each other over the years. |
| 1:18.3 | One of the areas in biohacking that has been on the roadmap forever, |
| 1:23.7 | but probably doesn't get enough notice or respect is vibration. |
| 1:29.7 | The definition of biohacking, when I started this movement, it's the art and science of |
| 1:35.0 | changing the environment around you and inside of you so you have full control of your own |
| 1:39.9 | biology. |
| 1:40.9 | And isn't it weird that vibration is a part of the world around you? And isn't it |
| 1:45.0 | where that vibration is something that is a primordial sense? You can feel if something's tapping |
| 1:50.7 | you. And you'll know if it's tapping you in a big way, like someone punching you. Or, you know, |
... |
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