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This Week in Cardiology

May 30 2025 This Week in Cardiology

This Week in Cardiology

Medscape Podcasts

Cardiology, Science, Medicalpractice, Electrophysiologist, Medscape, Internalmedicine, Medicaldecisionmaking, Expertcommentary, Eartrhythmdisorder, Health, Perspective, Medicine, Healthnews, Medicalexpert, Endoflifecare, Clinicaltrials, Health & Fitness

4.9876 Ratings

🗓️ 30 May 2025

⏱️ 31 minutes

🧾️ Download transcript

Summary

Listener feedback, CRT vs CSP, important clues on the ECG, beta-blocker interruption after myocardial infarction, novel approaches to LDL-C lowering, and ICD decisions in cardiac sarcoidosis are the topics John Mandrola, MD, discusses in this week's podcast.

This podcast is intended for healthcare professionals only.

To read a partial transcript or to comment, visit:

https://www.medscape.com/twic

I Listener Feedback

II CRT vs CSP – CONSYST-CRT

• Trial JACC EP https://doi.org/10.1016/j.jacep.2025.03.024

III The Important QRS

• Kewcharoen et al https://www.ahajournals.org/doi/10.1161/CIRCEP.125.013809

IV ABYSS Trial of BB Interruption after MI Continues to be Mis-interpreted

• ABYSS Main https://www.nejm.org/doi/full/10.1056/NEJMoa2404204

• ABYSS substudy https://doi.org/10.1093/eurheartj/ehaf170

• REDUCE AMI https://www.nejm.org/doi/full/10.1056/NEJMoa2401479

V Oral PCSK9i and the PURSUIT Trial

• Koren et al https://www.jacc.org/doi/10.1016/j.jacc.2025.03.499

• Editorial https://doi.org/10.1016/j.jacc.2025.03.518

Is Lifelong LDL-C Lowering Within Reach? The heart-1 Gene-Editing Trial https://www.medscape.com/viewarticle/998162

Heart-1 Gene Therapy Trial Pauses Enrollment https://www.medscape.com/viewarticle/998162

EHJ coverage VERVE https://academic.oup.com/ehjcvp/article/10/2/87/7455877

VI Cardiac Sarcoidosis and Risk of VT

• EHJ paper Mathijssen et al https://doi.org/10.1093/eurheartj/ehaf338

You may also like:

The Bob Harrington Show with the Stephen and Suzanne Weiss Dean of Weill Cornell Medicine, Robert A. Harrington, MD. https://www.medscape.com/author/bob-harrington

Questions or feedback, please contact [email protected]

Transcript

Click on a timestamp to play from that location

0:00.0

You're listening to This Week in Cardiology from the heart.org, Medscape Cardiology.

0:05.7

This podcast is intended for health care professionals only.

0:08.8

Any views expressed are the presenters' own and do not necessarily reflect the views of WebMD or Medscape.

0:14.9

Hi, everyone.

0:16.1

This is John Mandrola from the Heart.org Medscape Cardiology, and this is this week in cardiology for May 30th, 2025.

0:25.5

This week, listener feedback, CRT versus CSP, clues on the ECG, beta blockers after MI, novel approaches to LDL cholesterol lowering, and ICD decisions in cardiac sarcoidosis.

0:43.3

First up is some listener feedback. Dr. Steve Dixon, a heartfire cardiologist from Kansas City writes via email to pushback on my persistent skepticism about rapid titration of Godline-directed medical therapy in

0:57.6

hardfire.

0:58.9

SD says, I am right about the strong hardfire trial which used cardiologists for the majority

1:04.4

of follow-of visits.

1:06.5

And while cards-led care may currently be the case in many clinics across the country, he writes,

1:12.3

times are changing.

1:14.9

Hospitals, PCPs, and advanced practice practitioners are becoming more comfortable with these

1:20.0

life-saving medication classes.

1:22.9

And the future of heart failure care isn't just the burden of cardiologists, but internal medicine where there

1:29.2

are more reinforcements. Dr. Dixon says that in his clinic, they use a four-weeks four-meds program

1:36.7

for patients with Hefref, mainly through nurse practitioners that he guides and manage. He said it's

1:43.4

quite an aggressive program, but I can assure

1:45.5

you that my CEO of the hospital loves seeing his readmissions rates drop. Now my comment to this

1:52.9

is that I fully support programs like four weeks, four meds programs. It's a great idea. But of course,

1:59.6

this takes administrative support.

2:01.4

It takes champions, incentives.

...

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