May 23 2025 This Week in Cardiology

This Week in Cardiology

Medscape Podcasts

Cardiology, Science, Medicalpractice, Electrophysiologist, Medscape, Internalmedicine, Medicaldecisionmaking, Expertcommentary, Eartrhythmdisorder, Health, Perspective, Medicine, Healthnews, Medicalexpert, Endoflifecare, Clinicaltrials, Health & Fitness

4.9 • 876 Ratings

🗓️ 23 May 2025

⏱️ 22 minutes

🔗️ Recording | iTunes | RSS

🧾️ Download transcript

Summary

Listener feedback on sports “disqualification,” big digoxin news, Brugada syndrome, another positive finerenone study, and unblinded transcatheter trials are discussed by John Mandrola, MD, in this week's podcast.

This podcast is intended for healthcare professionals only.

To read a partial transcript or to comment, visit:

https://www.medscape.com/twic

I Listener Feedback

JACC EP Paper https://www.jacc.org/doi/10.1016/j.jacep.2025.03.013

II Digoxin News

DIGIT HF Baseline Characteristics paper https://doi.org/10.1002/ejhf.3679
DIGIT HF Rationale paper https://pmc.ncbi.nlm.nih.gov/articles/PMC6607489/
Dig trial https://www.nejm.org/doi/full/10.1056/NEJM199702203360801
DECISION trial https://onlinelibrary.wiley.com/doi/full/10.1002/ejhf.3428
Ziff et al BMJ meta-analysis https://www.bmj.com/content/351/bmj.h4451

III Brugada Syndrome

Gomes et al https://doi.org/10.1093/europace/euaf091

IV Another Finerenone Substudy Published

FINEARTS-HF trial substudy, Bhatt, A et al https://doi.org/10.1016/j.cardfail.2025.05.006
FINEARTS HF Main paper https://www.nejm.org/doi/full/10.1056/NEJMoa2407107
TOPCAT https://www.nejm.org/doi/full/10.1056/NEJMoa1313731
TOPCAT regional variation Circ paper https://www.ahajournals.org/doi/10.1161/circulationaha.114.013255

V Another Opinion on Unblinded Transcatheter Intervention Trials

Kaul https://eurointervention.pcronline.com/article/unblinded-trials-of-transcatheter-interventions-with-subjective-endpoints-what-are-the-implications

You may also like:

The Bob Harrington Show with the Stephen and Suzanne Weiss Dean of Weill Cornell Medicine, Robert A. Harrington, MD. https://www.medscape.com/author/bob-harrington

Questions or feedback, please contact [email protected]

Transcript

Click on a timestamp to play from that location

0:00.0	You're listening to This Week in Cardiology from the heart.org, Medscape Cardiology.
0:05.7	This podcast is intended for health care professionals only.
0:08.8	Any views expressed are the presenters' own and do not necessarily reflect the views of WebMD or Medscape.
0:14.9	Hi, everyone.
0:16.3	This is John Mandrola from the Heart.org Medscape Cardiology, and this is this week in cardiology for May 23rd, 2025.
0:26.4	This week, listener feedback on sports disqualification, big dejoxin news, Brugata syndrome, another positive phenaronone study, and unblinded trans catheter trials.
0:41.8	The first thing to say is that this is a holiday weekend in the U.S.
0:45.6	It's our Memorial Day where we honor our deceased men and women in the military.
0:50.2	As I've gotten older, my respect for those who died serving in the military has increased.
0:55.8	I am also off to Berlin AFIB today, and as such, this might be a slightly briefer podcast than normal.
1:02.5	First is listener feedback.
1:04.4	Paul Dorian, a senior Canadian academic EP, who has written extensively in the area of sports cardiology,
1:12.5	wrote to me via email regarding my comments on the Mayo Clinic Return to Play genetic heart disease study that I covered
1:18.2	last week. Dr. Dorian first agreed with my comments and the ideas of the authors who report
1:24.5	an extremely favorable prognosis of patients who were gene-positive but
1:30.1	phenotype negative disease. Let me quote from his email because it is so educational.
1:37.7	He writes, I take issue with the phrase disqualification. As sports cardiologist, we never, ever
1:43.8	disqualify any athlete from competing in sport.
1:48.1	Disqualification should be entirely restricted to the team, organization, or governing sport
1:52.9	entity for a particular sport. Disqualification is a legal and organizational concept. What physicians,
2:03.8	especially sports cardiologists, can and should do,
2:07.5	is inform the patient of the best estimate of the risk of sport,
	...

Please login to see the full transcript.

Previous episode | Next episode

Disclaimer: The podcast and artwork embedded on this page are from Medscape Podcasts, and are the property of its owner and not affiliated with or endorsed by Tapesearch.

Generated transcripts are the property of Medscape Podcasts and are distributed freely under the Fair Use doctrine. Transcripts generated by Tapesearch are not guaranteed to be accurate.