May 29 2026 This Week in Cardiology
This Week in Cardiology
Medscape Podcasts
4.9 • 963 Ratings
🗓️ 29 May 2026
⏱️ 29 minutes
🧾️ Download transcript
Summary
A life-long treatment for high LDL, a VESALIUS subanalysis, tirzepatide beats semaglutide again, arrhythmia burden in cardiac amyloidosis, and a lipid guideline rebuttal are the topics John Mandrola, MD, discusses in this week's podcast.
This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit:
https://www.medscape.com/twic
I Permanent Lipid Lowering therapy
- Verve 102 Therapy for FH https://www.nejm.org/doi/full/10.1056/NEJMoa2601283
II Vesalius Substudy on PCSK9i Use in Patients With Previous PCI
- VESALIUS Subgroup Analysis https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.126.080616
- VESALIUS Study - NEJM https://www.nejm.org/doi/full/10.1056/NEJMoa2514428
III Tirzepatide looking to be best again
- SURPASS-EARLY Trial https://www.acpjournals.org/doi/10.7326/ANNALS-25-05602
- SURMOUNT-5 Trial https://www.nejm.org/doi/abs/10.1056/NEJMoa2416394
IV Arrhythmias in Cardiac Amyloidosis
Loop Recorders Reveal Arrhythmias in Cardiac Amyloidosis https://www.medscape.com/viewarticle/loop-recorders-reveal-arrhythmias-cardiac-amyloidosis-2026a1000gq9
- EXCALIBUR Study https://www.jacc.org/doi/10.1016/j.jacc.2026.04.030
V Lipid Guidelines
· In Defense of the 2026 Dyslipidemia Guideline https://www.medscape.com/viewarticle/defense-2026-dyslipidemia-guideline-2026a1000hd0
- Lipid Guidelines: Four Major Concerns https://www.medscape.com/viewarticle/lipid-guidelines-four-major-concerns-2026a1000fim
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The Bob Harrington Show with the Stephen and Suzanne Weiss Dean of Weill Cornell Medicine, Robert A. Harrington, MD. https://www.medscape.com/author/bob-harrington
Questions or feedback, please contact news@medscape.net
Transcript
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| 0:00.0 | You're listening to This Week in Cardiology from the heart.org, Medscape Cardiology. |
| 0:05.4 | This podcast is intended for health care professionals only. |
| 0:08.8 | Any views expressed are the presenters' own and do not necessarily reflect the views of WebMD or Medscape. |
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| 0:37.7 | Medscape AI on the web or in the Medscape app. Medscape AI, trusted medical intelligence. |
| 0:41.6 | Hi, everyone. |
| 0:43.1 | This is John Mandrola from the Heart.org Medscape Cardiology, |
| 0:47.0 | and this is this week in cardiology for May 29th, 2026. |
| 0:51.8 | This week, a potential lifelong treatment for high LDL cholesterol, a vasilius |
| 0:58.1 | trial subanalysis, terseptide beats semaglutide again, arrhythmia burden in cardiac amelidosis, |
| 1:06.7 | and a lipid guideline rebuttal. I would like to first thank the Danish Cardiac Society for inviting me here to speak. |
| 1:14.3 | In Newbore, which I mispronounced last week as Nyborg. I know that I say it often, but I love Denmark. |
| 1:21.1 | As I record here in my hotel room overlooking the sea, I had to actually close the window because of the sea noises in the background. |
| 1:28.7 | It's no wonder that Danes are rated as one of the happiest people. This country is beautiful. |
| 1:33.5 | Now, it was imposing to speak to more than 300 Danish cardiologists because I know that they have |
| 1:39.7 | such a strong foundation and scientific appraisal of evidence. Yet, to my surprise, there are still a |
... |
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