Mar 14 2025 This Week in Cardiology

This Week in Cardiology

Medscape Podcasts

Cardiology, Science, Medicalpractice, Electrophysiologist, Medscape, Internalmedicine, Medicaldecisionmaking, Expertcommentary, Eartrhythmdisorder, Health, Perspective, Medicine, Healthnews, Medicalexpert, Endoflifecare, Clinicaltrials, Health & Fitness

4.9 • 876 Ratings

🗓️ 14 March 2025

⏱️ 28 minutes

🔗️ Recording | iTunes | RSS

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Summary

Listener feedback, resistant hypertension, K-binders for MRA use in heart failure, nutritional epidemiology, and a positive study for vitamin D are the topics John Mandrola, MD, discusses in this week's podcast.

This podcast is intended for healthcare professionals only.

To read a partial transcript or to comment, visit:

https://www.medscape.com/twic

I Listener Feedback

Califf editorial https://www.jacc.org/doi/10.1016/j.jaccas.2020.01.003

II Resistant HTN

Positive Topline Results for Lorundrostat in Hypertension

https://www.medscape.com/viewarticle/positive-topline-results-lorundrostat-hypertension-2025a100062e

III K-Binding

REALIZE K Trial https://doi.org/10.1016/j.jacc.2024.11.014
Packer Editorial https://doi.org/10.1016/j.jacc.2025.01.011
Diamond Trial EHJ https://doi.org/10.1093/eurheartj/ehac401
REALIZE K Commentary https://www.medscape.com/viewarticle/realize-k-new-potassium-binder-help-keep-spiro-board-2024a1000m2c

IV Butter vs Plant-based Oils and Mortality

JAMA-IM Study https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2831265
Is Red Meat Healthy? Multiverse Analysis Has Lessons Beyond Meat https://www.medscape.com/viewarticle/red-meat-healthy-multiverse-analysis-has-lessons-beyond-meat-2024a10008qv
Cookbook Review https://doi.org/10.3945/ajcn.112.047142

V Vitamin D

Impact Factor https://www.medscape.com/viewarticle/rare-win-vitamin-d-this-time-ms-2025a10005ul
D-Lay trial https://jamanetwork.com/journals/jama/fullarticle/2831270

You may also like:

The Bob Harrington Show with the Stephen and Suzanne Weiss Dean of Weill Cornell Medicine, Robert A. Harrington, MD. https://www.medscape.com/author/bob-harrington

Questions or feedback, please contact [email protected]

Transcript

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0:00.0	You're listening to This Week in Cardiology from the heart.org, Medscape Cardiology.
0:05.7	This podcast is intended for health care professionals only.
0:08.8	Any views expressed are the presenters own and do not necessarily reflect the views of WebMD or Medscape.
0:15.0	Hi, everyone.
0:16.3	This is John Mandrola from the Heart.org Medscape Cardiology, and this is this week in
0:21.9	cardiology for March 14th, 2025. This week I'll do some listener feedback, resistant hypertension,
0:30.6	potassium binders for MRI use and heart failure, nutritional epidemiology, and a positive study for vitamin D.
0:40.7	First up, some listener feedback. Last week, I strongly criticized a CAD trial, mostly on
0:48.8	methodologic grounds. The trial tested the use of CAC scoring, coronary calcium scoring, to reduce plaque volume in intermediate
0:57.9	risk patients with a family history of coronary disease. The trial was positive, but its trial
1:04.0	procedures precluded making any reliable clinical judgments. At least that was my argument.
1:13.7	This week, a Medscape journalist is working on a newspiece for the CAD trial, and he reached out to me for comment regarding a comments
1:19.8	the senior author made about my appraisal last week. Quote, I'm fascinated by the internet phenomenon
1:27.1	of opinion propagation.
1:29.4	There's no need to propose a solution to a problem just to denigrate any approaches other
1:34.2	than the status quo.
1:36.1	Nothing will ever change his mind because an outcomes trial with the required 20-year time
1:41.0	horizon will never be done.
1:43.7	Now, I'm not sure that this comment from the
1:46.3	senior author about my comments will make it into the news article, but I include it because it is a
1:52.2	comment I have heard from academic researchers before. In fact, the former FDA director, Dr. Robert
1:58.8	Caliph, once demeaned non-academic opinion writers on an internet
	...

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