4.4 • 984 Ratings
🗓️ 8 July 2025
⏱️ 47 minutes
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A new treatment for malaria in babies and very small children has just been approved; we hear more about the drug expected to save many lives.
Also in the programme: is Israel's new plan to create a so-called “humanitarian city” for Palestinians in Gaza from where they could “voluntarily” emigrate, actually legal? And a report on the environmental damage caused by China's rare earth mineral industry.
(IMAGE: The company logo is seen at the new cell and gene therapy factory of Swiss drugmaker Novartis in Stein, Switzerland, November 28, 2019. Novartis developed the new anti-malaria drug known as Coartem Baby or Riamet Baby in collaboration with the Medicines for Malaria Venture (MMV), a Swiss-based not-for-profit organisation initially backed by the British, Swiss and Dutch Governments, as well as the World Bank and the Rockefeller Foundation / IMAGE: Reuters / Arnd Wiegmann)
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0:00.0 | Hello and welcome to News Hour live from the BBC World Service in London. I'm Rebecca Kesby. |
0:09.4 | And for once, I'm delighted to say, we start the programme with some very positive news. |
0:14.3 | A medical breakthrough in the treatment of malaria. Well, in the treatment of malaria in babies and very small children at least, |
0:21.6 | and that's because a new soluble treatment has just been approved, specifically for babies. |
0:27.3 | It's the first time a malaria drug has been created for newborns, until now babies have either |
0:33.4 | not been treated or have been given very small amounts of drugs meant for older children, |
0:38.5 | but as well here, that's not ideal. |
0:40.7 | A short time ago, I spoke to Dr Caroline Bolton. |
0:44.1 | She's head of the Global Malaria Programme at Novartis, |
0:47.6 | which is the company behind the new drug. |
0:49.9 | She told me more about it. |
0:51.5 | Well, it is a really important new product for young babies with malaria |
0:56.9 | because it's the first malaria treatment that has been produced specially for this particular |
1:02.1 | patient population. And previously, the youngest babies in areas of malaria risk, when they |
1:09.3 | showed signs of malaria, they were given the products that |
1:12.8 | were designed for older children. And intuitively, you might think, okay, well, you just reduce the |
1:18.8 | dose, but actually young babies do not metabolize a number of drugs in the same way that adults do. |
1:25.0 | And that's the case for our particular anti-malarial. They get |
1:28.6 | extremely high levels of the active ingredients. And of course, that has the potential for toxicity. |
1:34.6 | And it's certainly not a great idea to overdose patients of that age group. So that's why we |
1:42.2 | decided to spend the time look for the right formulation to achieve |
1:48.4 | the right levels of the drugs in this youngest children, conduct a clinical trial. And actually, |
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