Team Zach here for med geeks your favorite podcast so today we're gonna do a quick

systematic review of lymphomas

Hodgkins and non-Hodgkins lymphoma after PA school I'm pretty sure all I knew about the topic

was that Reed Sternberg cells was associated with Hodgkin's lymphoma.

Maybe you're in the same boat right now, but after this podcast hopefully you'll have everything

you need to know for testing purposes. All right. Hodgkin's lymphoma.

Introduction lymphoid malignancy mainly derived from the B cell line, will find this Hodgkin's lymphoma

in the lymphatic system by its name characterized by Reed Sternberg cells, That's the buzzword there.

Normally begins at one lymph node

and progresses to adjacent lymph nodes

before it disseminates to other tissues and organs.

Follows a bimodal distribution distribution ages 20s to 30s and then once again it can

come back in the 50s slightly more common in men and overall it's a less common malignancy than non-Hodgans.

Ediology, its gene mutation, risk factors for our history of infectious mononucleosis

due to EBV, Epstein-Bar virus, history of

immune suppression, history of autoimmune disorders, family history and smoking.

Clinical presentation you get a painless localized enlarged

enlarged lymph node normally rubbery and mobile

and the super clavicular are clavicular regions and normally that's about

70% of the cases

or it's picked up by a metastinal mass on chest x-ray.

Non-specific B symptoms can also occur for clinical presentation,

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