4.8 • 688 Ratings
🗓️ 14 October 2025
⏱️ 47 minutes
🧾️ Download transcript
In this episode, Dr. Jockers sits down with longevity expert Dr. Isaac Jones to explore how oxidative stress accelerates aging—and what you can do to slow it down. Learn how mitochondrial health determines your energy, focus, and vitality, and why small daily habits have a massive impact on how you age.
You’ll also discover the “hallmarks of aging” and how lifestyle choices like diet, sleep, and mindset influence everything from inflammation to cellular repair. Dr. Jones shares the science behind epigenetics and how your environment and behavior can literally switch your longevity genes on or off.
Finally, dive into cutting-edge nutrition insights and longevity stacks designed to extend both your lifespan and healthspan. From mitochondrial boosters to antioxidant powerhouses, Dr. Jockers and Dr. Jones break down the nutrients and strategies that keep your brain sharp and your energy high well into later life.
In This Episode:
00:00 Understanding Oxidative Stress and Aging
02:34 Exploring Longevity and Aging
03:20 Meet Dr. Isaac Jones: Longevity Expert
04:16 Breakthrough Nutrients for Longevity
06:20 The Role of Epigenetics in Aging
08:12 Hallmarks of Aging and Their Impact
12:50 The Importance of Mitochondrial Health
18:57 Key Nutrients for Longevity
24:20 Maintaining Muscle Mass for Longevity
24:58 The Role of Gut Microbiome in Health
26:00 The Power of Pomegranate Extract
28:59 The Importance of Glutathione
30:29 Understanding PFAS and Their Impact
32:34 Creating a Synergistic Longevity Stack
39:36 Innovative Supplement Delivery System
44:23 Customizing Supplements for Individual Needs
45:37 Conclusion and Final Thoughts
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Looking to boost your digestion, immunity, and energy? Just Thrive Probiotic is the answer! Unlike most probiotics that get destroyed by stomach acid, Just Thrive is clinically proven to reach your gut 100% alive. This means better digestion, improved immunity, enhanced energy, and easier weight management. Plus, with their industry-leading 100% money-back guarantee, you’ve got nothing to lose. Save 20% off your order with code JOCKERS at justthrivehealth.com.
"Oxidative stress is like internal rusting—it’s the silent culprit behind aging, but we have the tools to combat it."
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Get 15% off Paleovalley: paleovalley.com/jockers – Use code JOCKERS
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| 0:00.0 | oxidative stress, which is inflammation in your body, builds up, and it causes apoptosis to |
| 0:06.1 | healthy cells that then leads to fibrosis. And he said it's the buildup of fibrosis, |
| 0:11.3 | which is fiber, fibrous tissue in the body that's kind of dead tissue, that leads to the |
| 0:16.6 | acceleration of aging because as it goes through the apoptosis process, you end up releasing all of |
| 0:23.6 | these toxins and chemicals within your body. This podcast is sponsored by our friends over at |
| 0:29.5 | Paleo Valley, and I love their grass-fed organ complex, which is like a supercharged |
| 0:35.6 | multivitamin. It allows you to get a full spectrum of traditional superfoods loaded with nutrients into |
| 0:42.0 | your body faster, easier, and without having to tolerate the taste. |
| 0:46.3 | Most people do not like the taste of liver, but traditionally it's the most nutrient-dense |
| 0:51.8 | food that people were eating, our ancestors were eating. |
| 0:55.5 | Now, grass-fed organ complex contains not one, but three organs from healthy grass-fed |
| 1:01.4 | pasture-raised cows, so you're getting a more diverse array of nutrients. |
| 1:05.8 | Most other similar products only contain one. |
| 1:08.2 | It's usually liver, and it's it's spray dried at high temperatures. |
| 1:12.1 | The ideal way to maintain the fragile nutrients and enzymes found in organ meats is to eat |
| 1:17.2 | them raw. |
| 1:18.2 | Again, not ideal for most people. |
| 1:20.5 | And so instead, Paleo Valley gently freeze dries the organs in order to preserve as many |
| 1:26.3 | of these nutrients as possible. And it comes in |
| 1:29.2 | capsules so you don't have to have the flavor. Now, liver is considered the most nutrient dense food |
| 1:34.2 | in the planet's full of B vitamins, vitamin A, minerals. Heart, which is in this as well, heart and kidney. |
| 1:39.9 | Heart is extremely rich in coenzyme Q10 and mitochondrial support nutrients for better energy, |
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