4.6 • 988 Ratings
🗓️ 20 September 2025
⏱️ 41 minutes
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| 0:00.0 | The 49ers will head into a key NFC West matchup on Sunday without their franchise quarterback again. |
| 0:12.7 | Mack Jones is in line for his second consecutive start in place of Brock Purdy who is limited all week in practices with the toe injury. |
| 0:20.1 | But will Purdy serve as the number |
| 0:21.9 | two or the number three quarterback on Sunday at Levi Stadium against the Arizona Cardinals? It's a |
| 0:27.9 | matchup of 2-0 teams and we're here to get you set for kickoff. Coach Kyle Shanahan sits down for |
| 0:33.9 | his weekly interview on 49ers game plan to preview this important early season |
| 0:38.9 | division showdown. And we will also check in with the man himself, Greg Papa, for another |
| 0:44.4 | installment of Ask Papa. We'll have all that and much more on this episode of 49ers talk coming at |
| 0:50.2 | you right now. Welcome to another episode of 49ers talk on NBC Sports Bay Area.com. |
| 0:58.1 | Introducing your hosts, Matt Mayoko and Jennifer Lee Chan. |
| 1:02.9 | All right, this is 49ers talk, brought you by Bigotires. |
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| 1:18.3 | Bigotires, the team you trust. |
| 1:20.9 | And I'm Matt Mayoko. |
| 1:21.9 | Jennifer Lee Chan is on assignment as we get ready for the 49ers and the Arizona Cardinals in a matchup of |
| 1:30.1 | two and O teams at Levi Stadium. And just because of where the schedule is right now, the 40 |
| 1:37.1 | in the Seattle Seahawks, the LA Rams are also 2 and 0. So the Rams, 49ers, and Cardinals head into week three with 2-0 records. |
| 1:47.7 | But as a result of that first-play schedule, winning the NFC West last year, the Rams will be going on the road to face the Philadelphia Eagles. |
| 1:57.7 | Not all of the NFC West teams play the same teams throughout this season. They're all |
| 2:04.4 | different as far as the NFC East, the NFC North, and the AFC North go. So this is the first |
| 2:13.2 | part of the schedule where the 49ers with the last place schedule sees a little bit of an |
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