meta_pixel
Tapesearch Logo
Log in
49ers Talk: A San Francisco 49ers Podcast

Eddy Piñeiro's game-winning field goal powers 49ers' gritty win over Cardinals in home opener

49ers Talk: A San Francisco 49ers Podcast

NBC Sports Bay Area

Nfl, Football, Matt Maiocco, San Francisco 49ers, Sports

4.6988 Ratings

🗓️ 22 September 2025

⏱️ 38 minutes

🧾️ Download transcript

Summary

The 49ers' home opener against the Arizona Cardinals brought plenty of twists and turns as San Francisco emerged victorious to maintain its undefeated start with a thrilling 16-15 win. Kicker Eddy Piñeiro's game-winning field goal and Mac Jones' clinical two-minute drive got the 49ers over the hump in a gutsy win, improving San Francisco to 3-0 in the 2025 season. The win didn't come without its costs as star defensive end Nick Bosa exited the game with an apparent knee injury. Matt Maiocco and Jennifer Lee Chan break down the 49ers' courageous victory, Bosa's injury and how San Francisco's alleged weakness in depth has turned into their strength as they now sit atop the NFC West standings.

Transcript

Click on a timestamp to play from that location

0:00.0

Savings. Big O savings.

0:03.0

Get up to $120 in savings and select Michelin Tires with installation purchase.

0:09.0

Plus, zero interest it paid in full within 12 or 6 months.

0:13.0

Big O Tires, the team you trust.

0:19.0

Stop us if you've heard this story before.

0:21.6

The 49ers had their rough patches on Sunday, but in the end they had just enough to pull out a close victory.

0:28.6

The 49ers followed the same recipe in week three against the Arizona Cardinals that worked so well in Seattle and in New Orleans.

0:36.6

And they sent their fans home happy with a narrow victory to remain as the lone unbeated team in the NFC West.

0:44.3

Fred Warner and the defense came through with a critical stop, and Mack Jones, making his second start in place of Brock Purdy,

0:51.3

engineered the drive that got the 49ers into position for Eddie

0:54.7

Penaero's winning kick. But as the 49ers left Levi Stadium Sunday night, there is also

1:00.2

concern about the status of Nick Bosa who left the game in the first quarter with a knee injury.

1:05.5

Jennifer Lee Chan and I will discuss all that and much more on this episode of 49ers talk

1:09.9

coming at you right now. Welcome on this episode of 49ers talk coming at you right now.

1:12.3

Welcome to another episode of 49ers talk on NBC Sports Bay Area.com.

1:18.3

Introducing your hosts, Matt Mayoko and Jennifer Lee Chan.

1:22.8

All right, this is 49ers talk brought to you by Big O Tires.

1:26.1

Drive away knowing you got the best deal on the road with Big O'Tires low price guarantee. Check out this week's specials and set an appointment at bigottyers.com. Big O'Tires, the team you trust. And boy, we're starting to get used to this. The 49ers win another close one. This time, another division matchup. They beat the Arizona Cardinals 16 to 15. Not a common score in the NFL, Jennifer, but it's turning into a common kind of way for the 49ers to win games. I walked out to Dominic Pony and I was like, you guys can't do this in an easy way, can't you? He's like, you got to make it hard. He's like, yep, that's what we're doing, but we're getting wins. So they are 3 and O and they are not making it easy on themselves. But also, when you think about it, the guys who are not in the lineup for them to get wins, they wouldn't have done this last year. So it's a definite difference in improvement over last season.

2:21.8

Yeah, I mean, one of the games last year that kind of set the 49ers down that path toward

2:27.5

final, you know, last place in the NFC West and a 1611 record was that game week five

2:33.2

at Levi Stadium against the Cardinals, where they get

2:36.6

outscored 14 to nothing in the second half. They're wearing the dark jerseys. That heat

...

Please login to see the full transcript.

Disclaimer: The podcast and artwork embedded on this page are from NBC Sports Bay Area, and are the property of its owner and not affiliated with or endorsed by Tapesearch.

Generated transcripts are the property of NBC Sports Bay Area and are distributed freely under the Fair Use doctrine. Transcripts generated by Tapesearch are not guaranteed to be accurate.

Copyright © Tapesearch 2025.