It's All in the Blood - Hereditary Spherocytosis
Medgeeks with Andrew Reid
Medgeeks
4.8 • 997 Ratings
🗓️ 9 September 2024
⏱️ 9 minutes
🧾️ Download transcript
Summary
In our upcoming hematology series, we'll delve into the fascinating world of genetic blood disorders. Our first episode will focus on Hereditary Spherocytosis (HS), a condition characterized by the production of abnormally shaped red blood cells resembling spheres instead of the usual disc-like shape.
We'll explore the underlying genetic mutation that causes HS and how it impacts the structure and function of red blood cells. Next, we'll discuss the common symptoms associated with HS, such as anemia, fatigue, jaundice, and abdominal pain. We'll also delve into the diagnostic process, including blood tests and genetic analysis.
Finally, we'll discuss the available treatment options for HS, which may include blood transfusions, medications, and in some cases, splenectomy.
Join Dr. Niket as we explore this rare genetic blood disorder and learn more about its impact on individuals and families.
September 9, 2024
Transcript
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| 0:00.0 | If you walk into any store these days, all you see are Halloween decorations, |
| 0:04.4 | unless it's Costco, which had the mountain May. |
| 0:06.8 | But that's besides the point. |
| 0:08.6 | Fall is nearly here, and with that come a host of fun holidays, of course the trick-or-treat season. |
| 0:15.0 | Many of us love the crisp cool mornings, the changing colors of the leaves, |
| 0:20.0 | and of course the element of something spooky in the air as Halloween is on the way. |
| 0:24.8 | And medicine is no less intertwined with Halloween as we've talked about previously in numbers of |
| 0:29.7 | podcasts, but there is one theme in all scary movies, and that's blood. That's right, when you talk about Dracula, he needs it to stay alive and many other things that go bump in the night use it as well. And so now we're going to start a new series, basically all about |
| 0:44.8 | blood. Now we're not going to necessarily be dealing with it in the sense of |
| 0:48.1 | spooky characters and things like I said that go bump in the night, but this new series is going to be all about |
| 0:53.7 | hematology and all the blood disgraceous inherited disorders and anemias and |
| 0:58.0 | coagulation problems to fill your heart's desire. I'm Dr. Niket Son Pal, your |
| 1:02.3 | friendly neighbor internist, |
| 1:03.6 | castrantroologist, and of course podcast host, and lover of fall more than the |
| 1:07.5 | Gilmore girls combined. Let's kick off that music and start the new series on, |
| 1:11.6 | it's all about the blood. Now our first disorder that we're going to be talking about this week is known as hereditary |
| 1:28.4 | spherositosis. It's actually very rare, but in fact it's the most common cause of hemelitic anemia |
| 1:35.2 | that has to do to a red cell membrane defect. So what's going on in this disorder and why are these red blood cells |
| 1:41.5 | hemilizing? Well, normal red blood cells or erythrocytes are bicon cave |
| 1:46.0 | and have good high plasticity |
| 1:48.0 | and they're able to get through the various vasculature |
| 1:50.0 | and so forth. |
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