How the microbiome affects metabolism and body weight | Dr Will Bulsiewicz, MD

The Proof with Simon Hill

Simon Hill

Nutrition, Health & Fitness, Self-improvement, Education

4.9 • 2.9K Ratings

🗓️ 21 August 2023

⏱️ 116 minutes

🔗️ Recording | iTunes | RSS

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Summary

Episode #275. Have you ever wondered how your gut health might affect your body weight? In this episode, I sit down with Dr Will Bulsiewicz – a leading authority in gut health and The Proof fan favourite – to unravel the fascinating connection between the microbiome and metabolism. From exploring dietary fibre’s impact on disease prevention to comparing ketogenic and plant-based diets, this conversation offers a deep dive into how our inner ecosystem influences our overall health. Tune in for actionable insights and scientific revelations that could transform your approach to wellbeing. Specifically, we discuss: Intro (00:00) Introduction to Dr. Will Bulsiewicz and His Literary Contributions (2:42) Do Gastroenterologists Analyse Their Own Stool? (7:43) Dr. Will Bulsiewicz's Collaboration with ZOE (9:55) Behind the Scenes: Dr. Will's Nutritional Supplement Venture (11:20) The Progressive Journey of the Gut Health Movement (14:02) Decoding the Microbiome: Its Role and Significance in Health (17:20) Exploring Metabolism and Metabolic Health (0:24:50) The Microbiome's Role in Influencing Metabolism (0:33:07) Understanding GLP-1 Agonists: Their Impact on Satiety and Weight Reduction (0:38:54) Tips to Increase Dietary Fibre Intake for Better Health (0:45:05) The Connection Between Microbiome and Fat Metabolism (0:47:36) Strategies to Boost Metabolism and Promote Brown Fat Activation (0:49:59) The Role of Lipopolysaccharide in Gut Barrier Functionality (0:51:33) Significance of Gut Health and the Risks of Dysbiosis (0:54:49) Linking Insulin Resistance with Satiety Mechanisms (0:56:03) The Relationship Between Satiety and Blood Sugar Fluctuations (0:58:30) Analysing Kevin Hall's Research: Plant-Based Diet vs. Alternative Diets (1:02:04) Blood Regulation, Insulin Resistance, Lipotoxicity, and Microbiome (1:10:38) Deciphering Glucose Homeostasis: What You Need to Know (1:20:37) The Interplay Between Insulin Resistance and Obesity Factors (1:21:51) The Beneficial Role of Dietary Fibre in Blood Sugar Management (1:23:11) Is Reversing Type 2 Diabetes a Possibility? (1:25:18) How the Microbiome Influences Blood Sugar Regulation Mechanisms (1:32:12) The Cholesterol-Lowering Benefits of Dietary Fibre (1:37:06) Top Sources of Soluble Fibre for a Healthy Diet (1:39:40) Triglycerides and Their Relationship with the Microbiome (1:42:06) The Protective Role of Fibre in Disease Prevention (1:46:28) Outro (1:51:46) Connect with Dr Will Bulsiewicz on Instagram, Facebook, Twitter, and TikTok. Discover more resources and Dr B’s books on his website, theplantfedgut.com, learn more about supplementation at 38tera.com, and find his work on personalised nutrition at joinzoe.com. Listen to Dr B’s past appearances on The Proof here. My team and I have also put together a PDF of resources for this episode, helping you better understand the science behind this conversation. Download it at theproof.com/drb. Optimise your health with InsideTracker’s biomarker analysis. Get exclusive access to InsideTracker’s new ApoB test, and a significant discount at insidetracker.com/simon. Head to The Proof website for supporting studies and the full show notes. Enjoy, friends. Simon Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends. You can also show your support by leaving a review on the Apple Podcast app and/or sharing your favourite episodes with your friends and family. Simon Hill, MSc, BSc (Hons) Creator of theproof.com and host of The Proof with Simon Hill Author of The Proof is in the Plants Watch the episodes on YouTube or listen on Apple/Spotify Connect with me on Instagram, Twitter, and Facebook Nourish your gut with my Plant-Based Ferments Guide Download my complimentary Two-Week Meal Plan and high protein Plant Performance recipe book

Transcript

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0:00.0	Finally, it's here, the Essential Prenatal Supplement by Emil.
0:09.3	I've been waiting for a prenatal supplement for pregnant women that's properly formulated
0:14.3	with the right ingredients and dosages for a long time.
0:18.6	Essential prenatal contains DHA, an important omega-3 during pregnancy, colon, vitamin B-12,
0:24.8	iodine, and other important nutrients in optimal dosages for pregnant women following a plant
0:30.7	predominant or exclusive diet.
0:33.5	Formulated by myself alongside previous show guest Dr. German Newman, nutritionist Jacqueline
0:38.4	Orwell, and naturopath Dr. Julie Chen, pregnancy is an extremely important life stage,
0:45.1	certainly a time to make sure that you're not falling short in your consumption of any
0:50.2	critical nutrients.
0:52.2	To learn more about essential prenatal and get 10% off your first order, head to the proof.com
0:58.0	forward slash friends.
0:59.6	That's the proof.com forward slash friends and follow the link to Emil's website.
1:08.1	Going back literally almost 20 years, one of the first microbiome studies involved the
1:13.2	transplantation of a microbiome from an obese human into a mouse and the discovery that that
1:20.9	mouse would become obese.
1:22.5	The microbiome is referring to a community of microorganisms and what you would see is
1:27.3	this flourishing community of all these unique different personalities bumping into one
1:31.6	and another, having conversations, making love, fighting with one another, trying to kill
1:36.7	each other.
1:38.7	It's much like a real life.
1:40.6	Being a gastroenterologist, do you inspect around stool, have a little chance?
	...

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