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Something You Should Know

How Ozempic and Similar Weight Loss Drugs Really Work & The Story of Money

Something You Should Know

Mike Carruthers | OmniCastMedia

Science, Social Sciences, Health & Fitness, Self-improvement, Education

4.64K Ratings

🗓️ 5 January 2026

⏱️ 48 minutes

🧾️ Download transcript

Summary

Can simply imagining yourself doing something actually make you better at it? Athletes, musicians, and performers have sworn by mental rehearsal for years — but does it really work? This episode begins by exploring when visualization helps, when it doesn’t, and why. https://www.popsci.com/will-practicing-skill-your-head-make-you-better-it/ Weight loss is one of the most common New Year’s resolutions — and today, any serious conversation about losing weight quickly turns to Ozempic and similar drugs. For many people, these medications have been remarkably effective. But how do they actually work? Are they safe long-term? What are the side effects? And what happens when you stop taking them? Aimee Donnellan joins me to break down the science, the risks, and the realities. She is a columnist at Reuters who covers the pharmaceutical industry and author of Off the Scales: The Inside Story of Ozempic and the Race to Cure Obesity (https://amzn.to/44tBoqE). Money is so embedded in our lives that we rarely stop to question it — yet nearly every culture on Earth has invented its own version. Money has shaped human behavior, powered civilizations, and driven innovation, for thousands of years. David McWilliams explains the extraordinary history of money and how it really works. He is a former central bank economist, host of The David McWilliams Podcast, and author of The History of Money: A Story of Humanity. (https://amzn.to/4anViHd). Cold weather can feel unbearable — but there are simple, science-backed ways to stay warmer (or at least feel warmer) when temperatures drop. This episode wraps up with practical strategies that actually work. https://www.thehealthy.com/home-remedies/make-body-feel-warmer/ Learn more about your ad choices. Visit megaphone.fm/adchoices

Transcript

Click on a timestamp to play from that location

0:00.0

This episode is brought to you by Shopify. With Shopify, 2026 is the year you make it happen. It gives you the tools to build your dream store, online and in person. Plus with marketing built in, it'll help you reach exactly who you need to. Join the millions who've already made the leap, like Jim Shark and all birds, and ring in the new year with Shopify.

0:23.3

Sign up for your £1 per month trial at shopify.com.uk slash Spotify.

0:31.9

Today on something you should know, if you imagine yourself doing something, can it make you better at

0:39.0

actually doing it? Then the latest on OZempic and other weight loss drugs, how they work

0:45.1

and their interesting side effects.

0:47.7

One woman I spoke to said that she loved eating takeout. Another guy spoke to love Diet Coke.

0:52.7

And when they were on these drugs, they had no interest in those types of foods.

0:56.2

They wanted salmon and vegetables and they'd go to grocery stores and they would spend most

1:00.7

of their money on fresh food.

1:03.4

Also effective ways to keep warm when you're in the cold and the fascinating history

1:08.7

of money and why it's often a difficult subject.

1:12.7

It is because money affects us in a different part of our psyche to logic,

1:18.7

taking the price of something.

1:20.1

Economists, when they see a price, they see a number.

1:23.6

When real people, normal people see a price, we get a feeling.

1:27.2

All this today on Something You Should Know.

1:30.3

Of the Regency era, you might know it as the time when Bridgeton takes place,

1:37.3

or it's the time when Jane Austen wrote her books.

1:40.3

The Regency era was also an explosive time of social change, sex scandals, and maybe the worst king in British history.

1:48.2

Vulgar History's new season is all about the Regency era, the balls, the gowns, and all the scandal.

1:54.3

Listen to Vulgar History, Regency era, wherever you get podcasts.

2:01.7

Something You should know.

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