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Dhru Purohit Show

How Overeating Sugar Shrinks Your Brain & The Unexpected Thing That Grows It

Dhru Purohit Show

Dhru Purohit

Medicine, Health & Fitness, Alternative Health

4.73.4K Ratings

🗓️ 29 September 2025

⏱️ 33 minutes

🧾️ Download transcript

Summary

This episode is brought to you by Bon Charge and AquaTru. Dwindling memory is often seen as a normal part of aging. But just because it’s common doesn’t mean it’s normal. There’s a lot we can do to safeguard the memory center of our brain, and it’s never too late to start. Today on The Dhru Purohit Show, we’re revisiting one of our most talked-about moments with Dr. Majid Fotuhi. He unpacks how excess sugar from a highly refined, processed diet can accelerate aging and damage key organs, including the kidneys, liver, and brain. Dr. Fotuhi also highlights animal studies linking sugar to brain decline, the blood markers we should all be monitoring, and practical strategies to support brain growth. Finally, he shares why having a strong sense of purpose is one of the most powerful ways to protect brain health. Dr. Fotuhi is a neurologist specializing in memory, concussion, and successful aging. With over 30 years of teaching, clinical practice, and neuroscience research at Harvard Medical School and Johns Hopkins, he has developed a multidisciplinary program to help people of all ages improve memory and attention. The results of his program have been published in numerous scientific journals as well as in his three books. Passionate about public education on brain health, Dr. Fotuhi also teaches in the Department of Psychological and Brain Sciences at George Washington University and at Harvard Medical School. In this episode, Dhru and Dr. Fotuhi dive into: Why sugar is so damaging to the brain (01:46) How elevated uric acid levels accelerate brain aging (11:22) Essential blood markers to monitor regularly (17:27) Key strategies to support brain growth (21:24) Why having a sense of purpose is vital for brain health (22:42) Final thoughts (30:35) Also mentioned: Full episode with Dr. Majid Fotuhi Try This: How Fructose Damages the Brain and Increases Our Risk for Alzheimer’s This episode is brought to you by Bon Charge and AquaTru. Right now, Bon Charge is offering my community 15% off. Just go to boncharge.com/DHRU and use code DHRU to save 15%. Aqua Tru is a countertop reverse osmosis purifier with a four-stage filtration system that removes 15x more contaminants than the bestselling water filters out there. Go to dhrupurohit.com/filter and get $100 off when you try AquaTru for yourself. Sign up for Dhru’s Try This Newsletter Learn more about your ad choices. Visit megaphone.fm/adchoices

Transcript

Click on a timestamp to play from that location

0:00.0

Hi, everyone, Drew Brode here.

0:01.5

You know, protecting our brains as we age is something that we all care about.

0:05.5

And it's a topic that I'm particularly passionate about exploring on this topic, which is why I'm

0:09.6

excited to share with you today a portion of an eye-opening conversation I had with a Dr.

0:14.6

Majid Fatoui that goes beyond the usual advice that we hear about brain health.

0:19.1

Dr. Fatoui is a neurologist with an expertise

0:21.8

in the fields of memory, concussion, and successful aging. Throughout his 30 years of teaching,

0:28.1

clinical work and neuroscience research at Harvard Medical School, and Johns Hopkins, he's developed

0:33.3

a multidisciplinary program for helping people of all ages improve their memory and attention.

0:39.2

And in today's conversation, we dig deep into something that's pervasive in our environment.

0:44.4

And we discuss how it negatively impacts our brain.

0:47.6

I'm talking about the excess sugar at pharmacological dosages that we're getting from sugary drinks and highly refined carbs

0:58.4

that make up a huge percentage of the average Americans diet. We're going to talk about how

1:03.3

excess sugar can not only shrink your brain over the long term, but more specifically how

1:08.9

it damages the hippocampus, the brain's memory center.

1:12.1

But this conversation isn't just about what hurts the brain. It's about what grows the brain as well.

1:16.7

Dr. Fatoui shares the science behind powerful lifestyle interventions that can literally increase

1:21.9

brain volume. From managing blood sugar and building lean muscle mass to getting better sleep

1:26.7

and even cultivating

1:28.2

a deeper sense of purpose in life. This episode, XER, is packed with practical insights and

1:33.9

hopeful takeaways. And it's one that all of us can benefit from. So let's jump right in with my

1:38.5

conversation with Dr. Majid Fatoui. You've repeatedly talked about how excess for two weeks.

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