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Chasing Life

How Far Would You Go to Replace Your Body? Mary Roach Has Thoughts

Chasing Life

CNN

Nutrition, Health & Fitness, Mental Health

4.4 • 7.8K Ratings

🗓️ 16 January 2026

⏱️ 26 minutes

🧾️ Download transcript

Summary

For centuries, humans have tried to repair and replace our body parts -- from brass noses and pig organs to today’s lab-grown tissue. So where do we stand now?  Sanjay sits down with author Mary Roach to discuss her newest book, Replaceable You: Adventures in Human Anatomy, which explores the wild history and newest experiments behind human “upgrades,” from 3D‑printed muscle to the ethics of elective amputation and what these innovations mean for our aging bodies.     Our show was produced by Jennifer Lai with assistance from Leying Tang.   Medical Writer: Andrea Kane Showrunner: Amanda Sealy Senior Producer: Dan Bloom Technical Director: Dan Dzula  Learn more about your ad choices. Visit podcastchoices.com/adchoices

Transcript

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0:00.0

You know, despite many years of practicing medicine and reporting on medicine, I am continuously

0:05.6

reminded that the body is still full of mysteries. Remarkable mysteries. We haven't figured out

0:12.4

how to stop aging or even why we really do age. We haven't cured cancer. There's really so much

0:18.3

about our bodies we don't know. Big fundamental questions.

0:22.5

And yet, at the same time, we've made real progress. Progress worth celebrating. We can replace

0:28.3

hips and limbs and heart valves and so much more. Just the whole notion of replacing pieces of

0:36.4

ourselves. How do we do that? Why do we do it? Where are we at?

0:40.8

That's one of my favorite science writers, Mary Roach. You're in for a treat today.

0:45.0

For years, she's explored big questions about the human body.

0:49.3

She's written about cadavers in her book Stiff.

0:52.6

The Science of Sex in her book Bonk. Yeah, she comes up with clever

0:56.5

titles. And even wrote about what happens to us in space in her book called Packing for Mars. This time,

1:04.0

however, she's turned her attention to humanity's long fascination with replacing body parts. And the book

1:10.7

is called replaceacable You.

1:14.1

So I really wanted her to come on the show. She accepted the invitation right away.

1:19.4

We're going to talk about what breakthroughs are already changing lives, what's still a work

1:24.0

in progress, and what it really means to replace parts of yourself that work

1:29.3

just as well, or maybe even better. I'm Dr. Sanjay Gupta, and this is chasing life. AI is incredible.

1:46.5

They can teach you how to fry an egg and even write a poem, pirate style.

1:51.5

But it knows nothing about your work.

1:55.8

Slackbot is different.

1:57.3

It doesn't just know the facts.

...

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