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Nutrition Facts with Dr. Greger

Healthy Aging with NAD+

Nutrition Facts with Dr. Greger

Michael Greger, M.D. FACLM

Alternative Health, Health & Fitness, Nutrition

4.83.7K Ratings

🗓️ 14 August 2025

⏱️ 15 minutes

🧾️ Download transcript

Summary

This coenzyme has a profound effect on our metabolism and aging process.

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Transcript

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0:00.0

Have you ever wondered if there are more natural ways to lower your high blood pressure,

0:06.0

guard against Alzheimer's, lose weight, feel better?

0:09.0

Well, it turns out there is.

0:12.0

Welcome to the Nutrition Facts podcast.

0:14.0

I'm your host, Dr. Michael Greger.

0:18.0

Today we look at the powerful properties of NAD Plus.

0:21.6

And no, it's not just another streaming platform.

0:24.6

NAD plus is an essential co-factor for hundreds of enzymes

0:28.6

with a potential role to play in the aging process.

0:32.6

Our understanding of nicotinide adenidid dinuclutid, NAD+, arose from humble beginnings as a factor

0:41.1

noted to enhance yeast fermentation in a 1906 paper unassumingly entitled, the alcoholic

0:47.8

ferment of yeast juice.

0:50.5

Little did they know that waves of NAD-related discoveries would go on to yield a total of four

0:55.4

Nobel Prizes. NAD Plus is now known as an essential molecule for all living organisms

1:01.4

required for the function of about 500 enzymes, including, notably, the extraction of metabolic

1:07.2

energy from food. The 21st century has produced yet another scientific renaissance for NAD

1:13.2

with the realization that it was critical for the activity of Sertuans,

1:17.1

the Guardians of Mammalian Health Span I detail in my book How Not to Age.

1:22.4

NAD is one of the most abundant molecules in our body,

1:26.4

once considered relatively stable,

1:28.0

it's now known to be in constant state of synthesis, recycling, and breakdown.

1:33.2

The entire pool of NAD and some of our tissues is termed over several times a day.

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