H-I-V...Not As Easy As 1-2-3: Eluding Vaccine Development for Decades

Unbiased Science

@unbiasedscipod

Education, Health & Fitness, Science

4.5 • 622 Ratings

🗓️ 25 January 2021

⏱️ 47 minutes

🔗️ Recording | iTunes | RSS

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Summary

This week we answer a commonly encountered question: "why were we able to develop a COVID-19 vaccine in less than a year, but don't have a vaccine for HIV?" We begin with the population health statistics of HIV globally to set the stage. We then do a primer on classification of viruses to underscore the fact that not all viruses are the same. We focus on SARS-CoV-2 and HIV specifically, and do a brief compare and contrast between the two viruses and virus families. We focus specifically on the challenges of vaccine development in the context of HIV: complexity of the virus itself, immune response to the virus, and disease pathology. We reiterate that the foundational research for the SARS-CoV-2 vaccine has actually been ongoing since 2002, and wrap up with our hope that someday we will be able to successfully develop an effective HIV vaccine. PLEASE NOTE: The discussion and information provided in this podcast are for general educational, scientific, and informational purposes only and are not intended as, and should not be treated as, medical or other professional advice for any particular individual or individuals. Every person and medical issue is different, and diagnosis and treatment requires consideration of specific facts often unique to the individual. As such, the information contained in this podcast should not be used as a substitute for consultation with and/or treatment by a doctor or other medical professional. If you are experiencing any medical issue or have any medical concern, you should consult with a doctor or other medical professional. Further, due to the inherent limitations of a podcast such as this as well as ongoing scientific developments, we do not guarantee the completeness or accuracy of the information or analysis provided in this podcast, although, of course we always endeavor to provide comprehensive information and analysis. In no event may Unbiased Science or any of the participants in this podcast be held liable to the listener or anyone else for any decision allegedly made or action allegedly taken or not taken allegedly in reliance on the discussion or information in this podcast or for any damages allegedly resulting from such reliance. Learn more about your ad choices. Visit megaphone.fm/adchoices

Transcript

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0:00.0	You're listening to an Airwave Media podcast.
0:04.6	Oh, that's my prime delivery.
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0:35.5	Yeah, oh, I am a scientist. Yeah, oh.K. slash prime. Welcome to unbiased science,
0:38.9	where we bring scientific method to the madness.
0:56.9	We're your hosts, Dr. Jessica Steyer and Dr. Andrea Love.
1:01.1	And this week, we are going to answer a question that we've heard from the herd many times.
1:09.4	And it's why were we able to develop a vaccine for COVID-19,
1:13.4	but haven't been able to for HIV? And, you know, Andrea, people ask us this with regard to
1:19.6	cancer and some other things too, but we wanted to focus specifically on HIV today. So before we
1:25.5	dive into that, I'll just briefly recap what we talked about last week.
1:30.3	So we dove into the science on, you know, whether we can and whether we should change the
	...

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