GLP-1 Protein Propaganda, Bethenny Frankel & Ketamine Treatments - 1299
The Chalene Show | Diet, Fitness & Life Balance
Chalene Johnson
4.8 • 7.3K Ratings
🗓️ 20 May 2026
⏱️ 57 minutes
🧾️ Download transcript
Summary
Three new GLP-1 studies, why every food is suddenly "high protein," the Bethenny Frankel shoe drama blowing up Instagram, and why I'm on a ketamine table as you listen.
Three new studies just shifted the GLP-1 conversation, and not in the direction women have been hearing about. Chalene digs into what's actually happening to muscle and bone density, why the rebound after coming off matters more than anyone's talking about, and the three questions every woman on Ozempic, Wegovy, Mounjaro, or Zepbound should bring to her next doctor's appointment.
She also gets into why every grocery aisle suddenly screams "high protein," and why this whole moment is starting to feel suspiciously like the Snackwell cookie era. There's a simple protein target that works without tracking macros, and Chalene walks through how she's using it.
Then she breaks down the Bethenny Frankel shoe drama that took over Instagram this week. What the shoe brand founder got wrong, what Bethenny got wrong, and the rules of brand partnerships that almost nobody outside the influencer world understands.
Finally, a personal update. As you're listening to this, Chalene is on the table for another medically supervised ketamine treatment with Dr. Andrew Levinson. She shares why she went back for a third session, what the last journey taught her about control, and who this kind of work is really for.
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🤓 Studies:
March 2026 — Weight loss with GLP-1 medicines does not result in a disproportionate loss of muscle mass or function in obese mice and humans
https://pubmed.ncbi.nlm.nih.gov/41850248/
March 2026 — Studies explore: GLP-1 receptor agonist use and its impact on long-term musculoskeletal health
May 2026 — Muscle atrophy associated with glucagon-like Peptide-1 receptor agonists: A population-based observational study
https://www.sciencedirect.com/science/article/pii/S0261561426000476
April 2026 — GLP-1 therapies and hair loss: A systematic review of current evidence and implications for counseling
https://pubmed.ncbi.nlm.nih.gov/41998799/
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Transcript
Click on a timestamp to play from that location
| 0:00.0 | What's up? Buttercup. Hey, happy Wednesday. I am so excited for you to listen to this episode. It's juicy. |
| 0:08.6 | I mean, we get really juicy. I'm going to talk about three different brand new studies about |
| 0:15.4 | GLP-1s that I think every single woman who's ever taken one needs to hear, especially. |
| 0:22.5 | Maybe you've never taken a gLP one. |
| 0:24.0 | If you've ever gone through a period of time where you had rapid weight loss, |
| 0:27.3 | or you know that you were under eating. |
| 0:31.0 | You weren't eating enough calories. |
| 0:32.8 | You weren't eating enough protein. |
| 0:34.4 | You need to hear about these studies because we're going to talk about what happens |
| 0:38.1 | to your bones in your muscles. And these new studies, I'm really excited that they're actually |
| 0:43.5 | looking at the impact this has on midlife women. Very, very important if you're someone who's |
| 0:50.6 | taking a GOP one. I am also going to break down the Bethany Frankl of it all. |
| 0:57.0 | There's major shoe drama. |
| 0:59.3 | Oh my gosh. |
| 1:00.3 | And I think I have a unique perspective on it. |
| 1:02.2 | I know everyone's talking about the fact that she undercut a female entrepreneur, |
| 1:08.5 | female founded footwear brand. I've got a unique perspective on this, |
| 1:15.3 | and it might surprise you. And if you don't know anything about what I'm talking or what I'm |
| 1:21.1 | referring to, don't worry. I'm going to play for you an audio clip from the woman who owns a shoe company, a brand, that she basically comes for |
| 1:37.6 | Bethany Frankel and says that Bethany Frankel is, quote, a weirdo. |
| 1:42.5 | I'm going to let you listen to this clip. |
| 1:44.9 | She basically threw the first punch. And Brett's going to, I'm going to play this for Brett |
... |
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