Friday Favorites: Fecal Transplants for Aging and Weight Loss
NutritionFacts.org Video Podcast
Michael Greger, M.D. FACLM
4.8 • 951 Ratings
🗓️ 20 March 2026
⏱️ 6 minutes
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Summary
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| 0:00.0 | Hippocrates said all diseases begin in the gut. |
| 0:14.4 | Previously, I've talked about fecal transplants, transferring the stool of healthy people |
| 0:19.5 | into the colons of patients suffering from |
| 0:21.6 | inflammatory bowel disease, multiple sclerosis, even psychiatric problems like depression, |
| 0:26.6 | bipolar disorder, and alcoholism to repopulate their gut with good bacteria in hopes of improving their conditions. |
| 0:34.6 | What about fecal transplants for aging? |
| 0:39.0 | Might the Fountain of Youth be a fountain of poop? |
| 0:43.1 | If you give mice with accelerated aging a fecal transplant from healthy mice, they perk up and |
| 0:48.3 | live longer, but what about human poop? |
| 0:51.7 | We don't yet have human-to-human aging data, but we do have mice transplanted with |
| 0:56.3 | fecal matter from a centenarian. |
| 0:59.3 | Mice-fed poop from a 101-year-old versus poop from a 70-year-old. |
| 1:04.0 | Lipophousin is an age pigment that's widely used as a biomarker for aging, and lipopherson |
| 1:08.9 | accumulates significantly less in the brain |
| 1:11.6 | tissue of centenarian poop-fed mice, raising the possibility that we will one day be using |
| 1:18.4 | centenarian fecal matter for anti-aging purposes and to promote healthy aging. |
| 1:24.2 | Why bathe in the blood of virgins when you can dine on the dung of the venerable? |
| 1:30.4 | To be continued once human-to-human data are published. |
| 1:34.3 | Poop you may want to avoid is from overweight stool donors, given this case report about weight |
| 1:39.7 | gain after a fecal transplant. |
| 1:41.9 | 32-year-old woman had always been of normal weight |
| 1:44.5 | until she received a fecal transplant from a healthy but overweight donor, her daughter. |
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