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Science Friday

Fish Eye Secrets, Human Genome Project, Science Diction 'Mesmerize.' Feb 12, 2021, Part 2

Science Friday

Science Friday and WNYC Studios

Science, Life Sciences, Wnyc, Natural Sciences, Friday

4.46.3K Ratings

🗓️ 12 February 2021

⏱️ 48 minutes

🧾️ Download transcript

Summary

Seeing The World Through Salmon Eyes The saying goes, “The eyes are the window to the soul.” But for fish, the eyes are the window to the stomach.  As one California biologist recently learned, the eyes of Chinook salmon are like a tiny diet journal of everything it ate. But to read that journal, you have to peel back the layers of the eye, like it’s the world’s tiniest onion.  Miranda Tilcock, assistant research specialist at the Center for Watershed Science at the University of California, Davis talks to Ira about why she goes to such gooey lengths to understand what these salmon eat.  Two Decades Beyond The First Full Map Of Human DNA In February 2001, the international group of scientists striving to sequence the human genome in its entirety hit a milestone: a draft of the complete sequence was published in the journals Nature and Science. The project took 13 years to complete: In that time, genome sequencing became faster and cheaper, and computational biology ascended as a discipline. It laid the groundwork for the greater cooperation and open data practices that have made rapid vaccine development possible during the pandemic. In the decades since, researchers have been trying to better understand how genetics impact health. We’re still working toward the dream of personalized treatments based on a person’s specific genetic risks. Ira looks back at the successes and challenges of the Human Genome Project with Shirley Tilghman, a molecular biologist who helped plan the project, and served on its advisory committee. Then, with bioinformatician Dana Zielinski and Indigenous geneticist-bioethicist Krystal Tsosie, he looks to the contemporary hurdles for genetic research, including privacy, commercialization, and the sovereignty of Indigenous peoples over their own genetic data. Meet The Man Behind The Word ‘Mesmerize’ In the 18th century, a man named Franz Anton Mesmer came to Paris with a plan: to practice a controversial form of medicine involving magnets and gravity. Mesmer claimed his treatments cured everything from toothaches to deafness. His critics, however, weren’t so sure about that. Mesmer made enemies in high places, labeling him a con, and calling his type of practice “mesmerism.”  The story behind the word “mesmerize,” and other words about mind control are the focus of season three of Science Diction, a podcast about words and the science behind them from Science Friday.  Joining Ira to talk about the story behind “mesmerize,” and what else is coming this season is Science Diction host, Johanna Mayer.

Transcript

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0:00.0

This is Science Friday. I'm Iroflato. If you're the squeamish type, you might want to prepare yourself for

0:05.9

this next conversation because we're going to talk about peeling eyeballs, fish eyeballs, that is.

0:12.7

Because you know how they say the eyes are the window to the soul? Well, for fish, the eyes are the window to the

0:19.6

stomach. Turns out that fish eyes are like a little tiny diet journal of everything that creature ate.

0:27.2

But to read that journal, you have to peel back the layers of the eye like it's the world's

0:32.6

tiniest onion.

0:34.0

But why would someone go to these lengths to understand what a fish ate?

0:38.5

Well, I'll have to ask my next guest.

0:40.6

Miranda Tilcock, Assistant Research Specialist at the Center for Watershed Science University of California at Davis.

0:48.5

Welcome to Science Friday.

0:50.3

Thank you for having me.

0:51.2

That was a great introduction.

0:53.2

So you can really do this. You can really

0:54.9

peel a fish's eye to find out what it ate. Exactly. So just like you said, they act as this

1:00.6

amazing little diet journal. And they're composed of each of these individual layers. And each of

1:06.5

these layers represent a different period in this fish's life history. And what you can do is you can then

1:12.5

put these pieces together to reconstruct their life, to see what they were eating. And if you know what

1:17.7

they're eating and if you understand the isotopes, these chemical fingerprints that are in our

1:23.2

environment, then you can then make meaningful interpretations for these individual layers in a fish

1:28.8

and better understand what they ate. And importantly, where were they eating that food?

1:34.2

Well, I understand that you study the Shaduk salmon in the California River system.

1:39.3

Tell us about why you want to study what the salmon are eating there.

...

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