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Science Quickly

Fight-or-Flight Nerves Make Mice Go Gray

Science Quickly

Scientific American

Science

4.2639 Ratings

🗓️ 15 February 2020

⏱️ 3 minutes

🧾️ Download transcript

Summary

A new study in mice concludes stress can cause gray hair—and credits overactive nerves with the change in hue. Karen Hopkin reports.  Learn more about your ad choices. Visit megaphone.fm/adchoices

Transcript

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0:00.0

Understanding the human body is a team effort. That's where the Yachtel group comes in.

0:05.8

Researchers at Yachtolt have been delving into the secrets of probiotics for 90 years.

0:11.0

Yacold also partners with nature portfolio to advance gut microbiome science through the global grants for gut health, an investigator-led research program.

0:19.6

To learn more about Yachtolt, visit yawcult.co.

0:22.7

.jp. That's y-A-K-U-L-T.C-O.jp. When it comes to a guide for your gut, count on Yacult.

0:33.6

This is Scientific Americans' 60-second science. I'm Karen Hopkin.

0:38.3

They say that Marie Antoinette's hair turned white the night before she lost her head to the guillotine.

0:44.3

But can stress really have such a dramatic effect on hair color?

0:48.3

A new study in mice concludes that it can,

0:51.3

and credits overactive nerves with stripping the color from the animal's

0:55.3

locks, and possibly ours. Researchers at Harvard's stem cell institute were interested in the

1:01.6

stress and hair color issue, so they decided to take a closer look at the stem cells that give

1:06.5

rise to melanocytes, the cells that pump pigments into each hair follicle.

1:11.5

The stem cells were an obvious target.

1:13.6

Because changes in the stem cell population translates to changes in hair color,

1:18.8

which are very visible and easy to identify.

1:22.2

Yace Su, the study's senior author.

1:25.2

To start, she and her colleagues subjected mice to some rodent-sized

1:28.8

stressors, like having their cage tilted, their bedding dampened, or their lights left on all night.

1:34.8

So what did we find? We found that stress indeed leads to premature hair grain in mice,

1:41.2

but it took a long time for us to actually narrow down how it occurs.

1:45.1

First, they thought it could be the immune system, attacking the melanocytes stem cell population.

...

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