Fertility Q&A - Low AMH, Hypothyroidism, Inflammation, and More!

As a Woman

Natalie Crawford

Medicine, Health & Fitness

4.8 • 1.1K Ratings

🗓️ 18 January 2026

⏱️ 16 minutes

🔗️ Recording | iTunes | RSS

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Summary

Dr. Natalie Crawford, board-certified OB-GYN and REI, answers your fertility questions. Questions Answered: 1. I’m 36 with an AMH of 1.1 and want three kids. I’ve lost 50 lbs on a GLP-1 but still have a BMI of 42. Should I try naturally now or focus on optimization first, and what’s the best plan for three healthy pregnancies? 2. I’ve been trying to conceive for 10 months and have a family history of Hashimoto’s. How does hypothyroidism affect fertility, and how can it be managed while trying to get pregnant? 3. I’m 40 with DOR (AMH 0.6, AFC 3–5) and about to start IVF. Is a dual stimulation approach right for me, should I bank embryos before transfer, and how many embryos are typically needed for one live birth? 4. I’m starting IVF for the first time. How important is the embryologist, and is it appropriate to meet them or tour the lab without overstepping? 5. I’m 33 with stage 4 endometriosis, prior excision surgeries, endometriomas, and a uterine polyp. What should I look for in an REI, and how can I reduce inflammation before egg retrieval and embryo transfer? Pre-order Dr. Crawford's debut book, The Fertility Formula, now! ⁠⁠https://www.nataliecrawfordmd.com/book⁠⁠ Want your questions answered on the next episode? ⁠Ask them here!⁠ https://www.nataliecrawfordmd.com/qa-submissions Learn more about your ad choices. Visit megaphone.fm/adchoices

Transcript

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0:00.0	Welcome back, friends, the As Woman podcast. I'm your host, Dr. Natalie Crawford, and today I'm joined by Emily Whitlock, and we are doing one of your favorite episodes, Fertility Q&A. I have no idea which ones are coming. So these are questions that you submitted. You can look for more information in the show notes about how you can submit your questions, so we can help you learn more about your fertility. Hey, M. Hi. Happy New Year. Happy New Year. Thanks for being here. I did not let Natalie
0:25.6	read these questions. So we are just going on a whim today. So the first one says she is 36. She has a 1.1
0:31.4	AMH. She wants three kids and she's not sure if that can happen naturally. She is on a GLP1 and has recently lost 50 pounds and knows that she should lose more weight,
0:41.1	but wants to start trying ASAP.
0:43.2	She wants to know your thoughts on the most beneficial plan to have three healthy pregnancies.
0:46.9	Okay, this is a great question.
0:48.6	First of all, congrats for weight loss.
0:51.8	And being on a GLP1 can be such an instrumental tool to decrease inflammation
0:55.9	and help people lose weight and keep the weight off. So that's a major milestone that's going to be
1:00.5	really impactful for health. However, I think it's important to note that 1.1 is a low AMH for her age
1:06.1	and be it at 36 wanting to have more than one child, we really want to think about what are the
1:12.6	odds of really achieving that third child. This is the perfect scenario where I recommend
1:16.7	seeing a fertility doctor and really thinking about embryo banking if we have a partner,
1:21.4	because this is going to put us in a position where even if we got pregnant today with baby
1:25.7	number one and we had our kids really close,
1:28.3	we're looking at being 40 or older for baby number three even if things go perfectly.
1:33.2	So putting some embryos into the freezer is going to be the top way to guarantee having three
1:38.0	children, be it that we have a low AMH now at age 36.
1:41.7	That would be the best plan if three kids is our goal.
1:44.9	Awesome.
1:45.4	Okay.
1:45.7	The second one says, my name is Jamie.
	...

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