The following episode originally aired in September of 2023.

And we really liked it then, and we really like it now.

So we thought maybe you'd want to hear it.

It's with Felicia Day. Enjoy.

If you break your leg, and I sure hope you don't, but if you break your leg,

that break in the leg bone is evident with the use of an x-ray.

You can see the break.

It's just a fact.

You have a broken leg.

Likewise, there are many diseases that will show up as a result of a blood test.

Chemicals go a certain way.

They read the report.

You have that disease.

Fact.

Something like depression is trickier. Frustratingly tricky for people who

experience it because there aren't a lot of objective binary standards in play. It doesn't show up on

x-rays or MRIs or CT scans. There's no depression chemical component that can be read conclusively in a lab.

And so we're left with a lot of emotional and behavioral cues. Does the person sleep an

inordinate amount, or not sleep much at all? Feelings of guilt or worthlessness, difficulty

concentrating or getting stuff done, do they have low energy, fatigue? Those could be

signs of depression, but someone could be depressed and not have those symptoms. Or someone could

have those symptoms and not be depressed. It's similar with anxiety disorders. You have a set of

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