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Wall Street Breakfast

Fate Therapeutics rises on Lupus drug data

Wall Street Breakfast

Seeking Alpha

Business News, News, Business, Investing

4.11K Ratings

🗓️ 19 November 2024

⏱️ 6 minutes

🧾️ Download transcript

Summary

Fate Therapeutics (FATE) closes 12% higher after soaring 73% on drug data (update). (00:25) Super Micro (SMCI) announces appointment of independent auditor, filing of compliance plan with Nasdaq. (02:11) Blackstone (BX) is said to near acquisition of Jersey Mike's sandwich chain. (03:02)

Episode transcripts seekingalpha.com/wsb.

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Transcript

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0:00.0

Welcome to Seeking Alpha's Wall Street Breakfast, where we cover the top news for investors every morning.

0:08.0

Good morning. Today is Tuesday, November 19th. I'm Julie Morgan.

0:13.0

Fate Therapeutics releases promising data on its lupus treatment.

0:17.0

Super microcomputer has a plan, and Blackstone is reportedly set to acquire a sandwich

0:23.6

chain. Fate therapeutics closed 12% higher on Monday after soaring as much as 73%. The increase was on the

0:32.7

news that the first patient in the company's phase one, autoimmunity study for its CAR-T-cell therapy candidate,

0:39.6

FT-819, is in remission for lupus six months after treatment. The company said the patient,

0:46.2

an African-American Asian woman, diagnosed with lupus nephritis, received fludarabine-free conditioning,

0:52.7

followed by a single dose of FT-819.

0:56.0

The woman achieved clinical remission as of the six-month follow-up,

0:59.9

free of all immunosuppressive therapies, as of the data cutoff date of November 11th.

1:05.4

The company said it is also enrolling a second treatment arm under the Phase 1 autoimmunity study to evaluate a single

1:13.0

dose of Ft819 as an add-on to maintenance therapy without conditioning chemotherapy in patients with a

1:20.8

different form of lupus. The new arm is being conducted in parallel with the study's conditioning arm.

1:27.2

Data from the Phase 1 studies was presented at the American College of Rheumatology

1:31.7

convergence meeting in Washington, D.C.

1:34.6

In a note Monday, BFA said it was upgrading its rating of the stock to neutral from underperform,

1:41.0

but keeping its price target at three bucks.

1:43.6

BFA said that while it viewed the update

1:45.8

as supporting the company's pivot from oncology to immunology, it would like to see additional

1:51.2

data for more patients before making changes to its model. BFA noted that fate has guided that it

1:57.6

will present additional data from the first three-dose patients at the American

...

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