Fasting Q&A with Dr Jason Fung: Off-Label Use of GLP-1s, Double Diabetes, Seed Oils, and More.

The Fasting Method Podcast

Megan Ramos Nutrition Inc

Nutrition, Health & Fitness

4.8 • 595 Ratings

🗓️ 27 May 2025

⏱️ 39 minutes

🔗️ Recording | iTunes | RSS

🧾️ Download transcript

Summary

Episode #206

In this Fasting Q&A episode, hosted by Coach Lisa Chance, Dr. Jason Fung answers questions from the TFM Community:

Are there common strategies that help to avoid the common pitfalls of Ramadan, like late night eating, overeating, or accidentally doing OMAD for too long and slowing down the metabolic rate? [01:07]
Concerns about off-label use of GLP-1s. Some medical professionals seem to be prescribing GLP-1 medications for anti-aging/longevity purposes in people who aren't overweight or diabetic. What do you think about the trend of "microdosing" GLP-1s as a preventative health measure? [02:36]
Are there further short and long-term side effects of GLP-1s coming to light? [06:36]
Are there ethical concerns around supply issues with GLP-1s due to increased demand from off-label use? [ 10:12]
Are there bioethical concerns about GLP-1s that doctors should be discussing with patients? [12:03]
Can you address how people with Type 1 diabetes can develop insulin resistance similar to those with Type 2, sometimes referred to as 'double diabetes'? [16:21]
How concerning is an elevated Lp(a) and how can you lower it? [20:47]
Do you know of research or trials with fasting to reduce prostate size? [26:28]
Can someone who is considering kidney donation fast/fat fast? [29:08]
I'm seeing many reputable sources saying that the claims against seed oils aren't actually based in the science. I'm curious whether Dr. Fung's opinion has evolved on this? [30:51]

Links

A Conversation with Dr. Tro Kalayjian

https://youtu.be/2Vuhip2UlTs?si=fxHBpgNkcI65SOrV

Cholesterol Ration Calculator - Omni Calculator

https://www.omnicalculator.com/health/cholesterol-ratio

Please note that you need to be a member of the TFM Community to submit questions to the Q&A webinars with Dr. Fung but you can submit questions to our regular Q&A episodes here: https://bit.ly/TFMPodcastQs

Transcripts of all episodes are available on the Podcast page at www.thefastingmethod.com

https://www.thefastingmethod.com/masterclasses-and-live-workshops-2025/#FFMC

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Summary Timestamps

00:00 Intro

01:07 Fasting Strategies for Ramadan

02:36 GLP-1s for Off-Label Use

06:36 Side Effects of GLP-1s

10:12 Ethical Concerns with GLP-1 Supply Issues

12:03 Bioethical Concerns GLP-1s

16:21 Type 1 Diabetes and IR

20:47 Lp(a)

29:08 Kidney Donation and Fasting

30:51 Seed Oils

Disclaimer

This podcast is for educational purposes only and is not a substitute for professional care by a doctor or other qualified medical professional. You should always speak with your physician or other healthcare professional before doing any fasting, changing your diet, taking or adjusting any medication or supplements, or adopting any treatment for a health problem. The use of any other products or services purchased by you as a result of this podcast does not create a healthcare provider-patient relationship between you and any of the experts affiliated with this podcast. Information and statements regarding dietary supplements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent any disease.

Transcript

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0:00.0	The most powerful predictor, the strongest association by far and away is the HDL and triglycerides.
0:07.9	And that is the one that is the most affected by diet, specifically carbohydrates.
0:15.6	So if you reduce your carbohydrate intake, you can reduce your triglycerides and raise your H.T.L., which is extremely,
0:23.3	extremely powerful in predicting heart disease.
0:33.0	Hello, everyone. My name is Lisa Chance, and I'm a fasting coach here at the fasting method,
0:38.6	and we are here today with our very own Dr. Jason Fung for our monthly Q&A.
0:43.7	This is a monthly Q&A with Dr. Fung, where he answers questions submitted by our
0:49.3	TFM community members. So hello to our podcast listeners that we'll be able to listen to this a few weeks after our community members. So hello to our podcast listeners that will be able to listen to this a few
0:55.8	weeks after our community members. All right. So I'm going to dive right in. Good morning, Dr. Fung.
1:02.8	Hi, good morning. It's great that you're here. I've got several questions for you. One is,
1:07.8	are there common strategies that help to avoid the pitfalls of Ramadan, late night eating,
1:14.6	overeating are accidentally doing OMAD for too many days in a row and slowing down the metabolic rate?
1:23.4	I mean, just the usual precautions you have to take about overeating.
1:27.7	The main thing is, you know, a lot of people during Ramadan, you don't eat during the day
1:32.2	and then you eat at night.
1:33.3	So what happens is that some people tend to prepare a huge meal and stuff, which is sort of
1:39.0	one of the big pitfalls, right?
1:40.8	Because if you're not eating during the day or allowing your body to use up the
1:45.2	calories, but then eat a huge meal at night with lots of sugary stuff and refined foods and so on,
1:51.8	then you're sort of undoing a lot of the good. So you want to eat as normally as possible.
1:57.1	So it's the same idea, like just try to make it a routine. And the good thing about doing it for a month is that if you can do it for a month, then it sort of establishes a new habit. Eating late at night is not a great idea anyway. So it's good to try and keep that as low as possible. Because, of course, you eat all that and then you go to sleep. Well, what is your body going to going to do with it right it's difficult for it to do anything other than store it which is a problem yeah that's my pitfall when i when i eat late at night
2:26.7	dr fun that's when i gain the weight and when i stop eating late at night that's when i lose the weight's, for me, it's a big one of the five pillars.
	...

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