Exploring the Link Between Niacin and Fatty Liver Disease

Dr. Joseph Mercola - Take Control of Your Health

Briana Mercola

Alternative Health, Health & Fitness

4.6 • 1.6K Ratings

🗓️ 24 February 2026

⏱️ 14 minutes

🔗️ Recording | iTunes | RSS

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Summary

Fatty liver disease is the most common liver disorder, driven by obesity, Type 2 diabetes, and insulin resistance. It often progresses silently for years before symptoms appear
Niacin helps your body use energy better. It turns down a molecule called microRNA-93, which normally blocks two key proteins that help your cells make energy and burn fat. By restoring those proteins, niacin helps your mitochondria work more efficiently. This shift supports fat burning in your liver instead of fat storage
Higher niacin intake has been linked to reduced liver fat, lower inflammation, improved insulin sensitivity, better cholesterol levels, and reduced long-term mortality in fatty liver patients
Niacinamide is the better choice compared to niacin because of its function as an NAD+ precursor. The ideal dosage is 50 milligrams three times a day, ideally in powder form for precise intake. Niacinamide also doesn't cause skin flushing
Increasing choline intake is the best way to manage fatty liver disease. Research shows it helps transport fat out of the liver. While there are several types of choline supplements available, citicoline is the preferred one because of its high bioavailability

Transcript

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0:00.0	What if I told you that the most common disorder affecting your body's primary filter
0:04.0	could be progressing inside you right now, completely silently, for years before you ever noticed a single symptom?
0:12.0	Welcome to Dr. Mercola's cellular wisdom.
0:16.0	Stay informed with quick, easy-to-listen summaries of our latest articles, perfect for when you're on the go.
0:21.6	No reading required. Subscribe for free at Mercola.com for the latest health insights.
0:26.6	Hello and welcome to Dr. Mercola's cellular wisdom.
0:31.6	Today we are turning our attention to a really crucial topic, one that touches on metabolic health, these hidden processes in our bodies, and a very specific nutrient connection.
0:43.3	It's good to be here. This is one of those topics that, you know, it really highlights why we need to look closer at what's happening on a cellular level.
0:50.3	Yeah, absolutely.
0:51.3	We aren't just talking about like stomach ache or feeling a bit tired. We're talking about the underlying mechanics of how your body processes energy.
0:58.0	And the silent toll it takes when that processing goes wrong.
1:01.0	Exactly.
1:02.0	So our mission today is to unpack the story here.
1:05.0	We want to understand just how widespread fatty liver disease actually is and, you know,
1:10.0	identify the key drivers.
1:12.3	Things like insulin resistance.
1:13.8	And really look at that connection to niacin that's hinted at.
1:17.5	We're analyzing a report by Dr. Joseph Mercola and honestly, there's a lot more here than
1:23.1	meets the eye.
1:24.5	It's not just a medical report.
1:26.0	It's almost a detective story about our own biology.
1:28.3	Oh, there certainly is. It's a concise report. But the implications of the points raised are just massive.
	...

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