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High Intensity Health with Mike Mutzel, MS

Exercise Causes Muscle to Make Fat Burning Hormones Called Exerkines

High Intensity Health with Mike Mutzel, MS

Mike Mutzel

Nutrition, Medicine, Health & Fitness

4.71.3K Ratings

🗓️ 5 August 2022

⏱️ 19 minutes

🧾️ Download transcript

Summary

Researchers are discovering how exercise causes muscles to make fat burning hormones and molecules called exerkines. In this show we dive into the details about the health benefits linked with exercise and exerkines.


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Link to references and show notes: https://bit.ly/3QoKbQT

Time Stamps

0:00 Skeletal muscle is an endocrine organ.

0:10 Movement stimulates your skeletal muscle organ to release endocrine-like hormones and myokines (aka exerkines) that have systemic effects upon the brain, heart, liver, bone, mood, and more.

1:10 Movement/exercise can have anti-cancer properties.

1:50 Increases in exerkines influence microRNA increases.

2:40 Skeletal muscle is the largest organ of your body by weight.

4:55 Volume and intensity of exercise determines the duration and quantity of release of exerkines.

5:15 Start: Do 3 to 5 exercises for 3 to 5 reps, 3 to 5 sets, 3 to 5 days per week. Do the things you like.

6:00 Exerkines have paracrine and autocrine effects that effect muscle, the entire endocrine system, fat cells, immune system, bone, and brain.

7:30 Habitual exercise can induce sustained elevated increase in exerkines and the associations with disease reduction.

10:15 After exercise, there is a transient increase in proinflammatory interleukins, and a post exercise increase from skeletal muscle with systemic anti-inflammatory properties.

12:10 The anti-cancer effects of exercise go beyond the reduction in bodyfat.

13:30 Exerkine milieu lasts for several hours after exercise cessation.

14:05 Exercise can prevent or delay the onset of neural degenerative conditions.

15:30 Adipose tissue can release exerkines.

16:10 Your liver is a major source of many acute and chronic exercise-responsive cytokines.

17:10 Exercise affects your gut microbiome.

Transcript

Click on a timestamp to play from that location

0:00.0

Hey friends, welcome back.

0:01.0

So, new science suggests that skeletal muscle is an endocrine organ just like your thyroid

0:05.6

or your adrenal glands or even your pancreas.

0:07.6

Now, we're going to talk a little bit more about how exercise and movement is required

0:12.1

to stimulate this organ known as skeletal muscle to release various endocrinological-like

0:17.5

hormones and myokines, also known as exercines.

0:21.4

We're going to take a deeper dive into how exercise and movement causes your muscle to release

0:26.3

hormone-like mediators that have systemic effects on the brain, on the heart, on the liver,

0:31.4

on the cardiovascular system in general, on bone, on mood, affect.

0:36.2

I mean, there's so many different aspects here with regards to how exercise stimulation

0:41.1

upon skeletal muscle causes this organ to have systemic health-promoting effects independent

0:47.4

of calorie burning, independent of, say, resistance training or some of the modalities associated

0:52.5

with exercise.

0:53.8

It's really important to understand this.

0:55.6

Now, when you think, just comparing and contrasting before we dive into the details from this

0:59.9

paper titled, extra kinds in health resilience and disease, it's free right on the internet.

1:05.1

I'll link it in the show notes.

1:06.3

I highly recommend you check this out, even if you're not interested in exercise because

1:11.2

understanding how skeletal muscle is an organ will help you make better habits and

1:16.6

lifestyle choices.

1:17.6

When you're a little bit tired and you think, well, I shouldn't go to the gym today because

1:21.3

I'm tired or maybe I don't have the energy within me to go for a walk with my dog.

...

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