Everything You Need to Know About Creatine w/ Dr. Eric Trexler
RP Strength Podcast
Dr. Mike Israetel, Nick Shaw
4.7 • 582 Ratings
🗓️ 17 November 2025
⏱️ 68 minutes
🧾️ Download transcript
Summary
Want to get even more jacked? Grab the RP Hypertrophy App for your training, and maximize your gym efforts with the RP Diet Coach App to nail your nutrition.
00:00 – How many PhDs (1.5-2.5)? +/- Medical Dr.
02:30 - CPR & broken ribs
04:30 - How Mike's cheeks were shot off
15:54 - How fast does creatine start working?
23:30 - Top end dosage of caffeine
28:20 - Best form of creatine/dose
31:10 - Should you cycle creatine?
33:30 - Lower vs higher dosing
37:45 - Does creatine negatively affect kidney function?
44:00 - Does creatine help with brain function?
47:45 - What kind of results should you expect from creatine?
56:15 - Downsides of creatine supplementation
01:02:00 - Wrap up
Transcript
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| 0:00.0 | Welcome, everyone to the RPSR strength podcast. |
| 0:06.1 | I am Nick Shaw, joined by two doctors, two doctors, Dr. Mike Isratel, Dr. Eckstall. |
| 0:13.8 | Dr. Xerxler. |
| 0:15.1 | What's up, guys? |
| 0:16.7 | Isn't it more like a doctor and a half best? |
| 0:21.4 | Hey, some people have called me a PhD before, so maybe I get an honorary half one. |
| 0:25.4 | Oh, you're right. |
| 0:26.5 | Okay, so we're back to two. |
| 0:27.4 | Okay, well, between one and a half and two and a half. |
| 0:30.5 | That's kind of our confidence interval there. |
| 0:32.7 | Yeah. |
| 0:33.7 | Yeah, some doctors almost certainly, probably around two, but uncertain as to the exact |
| 0:41.7 | boundary layers therein. Plus, Eric, you know, your doctor is in some serious shit. It's |
| 0:49.2 | probably worth a little bit more than the average PhD. You know, this is totally meaningless, but it technically came from the School of Medicine |
| 0:56.7 | at UNC. |
| 0:58.2 | So I sometimes mislead people and talk about back in med school when I was becoming a doctor, |
| 1:04.2 | and both of those are true and extremely misleading and create a lot of scope of practice issues. |
| 1:10.5 | You know what would be funny in a very morbid way? The following is a joke that you're sitting in a really long international flight and you're just talking to someone next to you, good vibes, bullshit. |
| 1:23.6 | And you say what you just said, like, oh, I was a medical school and then I got a doctorate. |
| 1:29.3 | And then someone like starts passing out next to you. |
| 1:32.3 | And they're like, help him. |
| 1:33.3 | And you're like, I'm not a medical doctor. |
... |
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