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STEM-Talk

Episode 62: Keith Baar talks about muscle and explains mTOR, PGC-1a, dystrophin, and the benefits of chocolate

STEM-Talk

Dawn Kernagis and Ken Ford

Natural Sciences, Science, Alternative Health, Health & Fitness, Nutrition

4.7706 Ratings

🗓️ 24 April 2018

⏱️ 63 minutes

🧾️ Download transcript

Summary

Today’s episode is the first of a two-part interview with Dr. Keith Baar, the head of the Functional Molecular Biology Laboratory in the Department of Neurobiology, Physiology, and Behavior at the University of California, Davis. In his capacity as a researcher, Keith has made fundamental discoveries on how muscle grows bigger, stronger, and more fatigue resistant. He is a renowned scientist in the emerging field of molecular exercise physiology, and is leading a team of researchers attempting to develop ways to improve muscle, tendon and ligament function. Part one of our interview features our conversation with Keith about his background and his time time in the lab of John Holloszy, who is known as the father of exercise research in the United States. Episode 63 of STEM-Talk has Dawn and Ken talking to Keith about his most recent research, which is looking at how to determine the best way to train, as well as what types of foods compliment training to decrease tendon and ligament injury and accelerate return to play. This work has the potential to improve muscle function and people’s quality of life, especially as they age. Ken and Dawn also have a conversation with Keith about the research he is doing on a ketogenic diet and its potential to reduce cancer rates and improve cognition. Links: UC Davis physiology department bio: https://www.ucdmc.ucdavis.edu/physiology/faculty/baar.html UC Davis biology department bio” https://biology.ucdavis.edu/people/keith-baar Functional Molecular Biology Lab website: http://www.fmblab.com Molecular brakes regulating mTORC1 activation in skeletal muscle paper: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4137116/ Age-related Differences in Dystrophin article: https://www.ncbi.nlm.nih.gov/pubmed/27382038

Transcript

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0:00.0

Welcome to STEM Talk.

0:01.2

Stem Talk.

0:01.8

Stem Talk.

0:03.3

Stem Talk.

0:03.7

Stem Talk, where we introduce you to fascinating people who passionately inhabit the scientific and technical frontiers of our society.

0:14.0

Hi, I'm your host, Don Cornagas, and joining me to introduce today's podcast is the Man Behind the Curtain, Dr. Ken Ford, IHMC's director and chairman of the

0:21.8

double secret selection committee that selects all the guests who appear on STEM Talk.

0:25.8

Hi, Dawn. Good to be here.

0:27.9

Dr. Keith Barr is the head of the functional molecular biology laboratory in the Department of Neurobiology,

0:33.3

physiology, and behavior at the University of California, Davis.

0:36.9

He is a renowned scientist in the emerging field of molecular exercise physiology and is leading

0:41.5

a team of researchers attempting to develop ways to improve muscle, tendon, and ligament function.

0:46.8

Our interview with Keith went more than two hours, so we decided to divide our conversation

0:50.8

with Keith into two parts.

0:52.4

In part one of our interview, we talked to Keith about some of the fundamental discoveries

0:56.8

that he has made on how muscle grows bigger, stronger, and more fatigue resistant.

1:02.4

In part two of our interview, we will be talking to Keith about his most recent research,

1:06.2

which is looking at how to determine the best way to train and what types of foods complement

1:10.3

training to decrease tendon and ligament train and what types of foods complement training to decrease

1:11.4

tendon and ligament injury and accelerate return to play. This work not only has a potential to improve

1:17.1

muscle function, but also can improve people's quality of life, especially as we age. But before we

1:22.7

get to today's interview with Keith, we have some housekeeping to take care of. First, we really

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