Episode 278: Journal Club 6: A Re-Analysis of DIETFITS
Low Carb MD Podcast
Drs. Brian Lenzkes & Tro Kalayjian
4.8 • 1.2K Ratings
🗓️ 8 May 2023
⏱️ 58 minutes
🧾️ Download transcript
Summary
Thank you for joining us for another episode of the Low Carb MD Podcast's Journal Club.
Dr. Matt Calkins is an emergency medicine resident who loves studying the science of longevity, the optimization of all phases of health, and applying his knowledge to physician and patient wellness. Matt earned his M.D. from the University of Florida and holds a B.Sc. in physics.
In this conversation, Tro and Matt talk about the conclusions, parameters, and methods of the DIETFITS study, what can be reasonably concluded from this study and what cannot, some of the weaknesses in the design of the study, conflicts of interest with the lead author of the study, the findings of a recent re-analysis of the DIETFITS study, and some important distinctions between what can be learned from clinical trials and what is observed in clinical practice.
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Transcript
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| 0:00.0 | Welcome to the Low-Carb MD Podcast. |
| 0:03.8 | No one is beyond help. |
| 0:05.8 | No one is beyond hope. |
| 0:08.5 | As we have always said, we are bringing you medical information and cutting-edge science, |
| 0:12.7 | but none of this is medical advice. |
| 0:15.7 | Please seek out input from your own doctor. |
| 0:18.8 | Hi everybody, welcome to the Low-Carb MD Podcast. |
| 0:28.7 | We have another episode of Journal Club where we are joined by the esteemed Dr. Matt Cawkins. |
| 0:35.4 | And we are going to be talking today about, we're going to be talking about diet fits and |
| 0:42.5 | the diet fits analysis. |
| 0:44.1 | Just so everybody knows what diet fits is, let's give everybody a backstory. |
| 0:49.4 | So let's start about 15 years ago, 20 years ago, where a Stanford researcher by the name |
| 0:54.6 | of Christopher Gardner, who is now the lead of the dietary guideline. |
| 0:58.6 | He is now the lead of the dietary guidance committee, decided to do two major trials. |
| 1:06.2 | The first trial was the A to Z trial, was the head-to-head trial. |
| 1:09.5 | This is back in 2007 or 2005, I believe. |
| 1:13.0 | The A to Z trial was probably one of the most notable trials where he compared Atkins |
| 1:19.4 | to Zone to Ornish and I think there was one other trial arm there, but he did a head-to-head |
| 1:27.3 | trial. |
| 1:28.8 | So I tried to determine who should win the Diet Wars, and this is back in 2007, and what |
| 1:34.2 | he found was Atkins just demolished everybody else, and this was published in the England |
| 1:40.4 | Journal. |
... |
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