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The Science of Everything Podcast

Episode 155: Embryology and Development

The Science of Everything Podcast

James Fodor

Social Sciences, Natural Sciences, Science

4.8819 Ratings

🗓️ 24 October 2025

⏱️ 70 minutes

🧾️ Download transcript

Summary

An introduction to the process of development, beginning with fertilisation and covering the stages of blastocyst formation, implantation into the uterus, gastrulation and its constituent cell movements, neurulation and the role of the notochord, and the beginnings of organogenesis. We also discuss the differences in gastrulation between protostomes and deuterostomes, along with the many specialised structures found in amniotes to protect the growing embryo from drying out. We conclude with overview of some of the genetic mechanisms government the development process, including Hox genes and their role in governing genetic regulatory networks. Recommended prelistening is Episode 25: Tissues, Organs, and Systems. If you enjoyed the podcast please consider supporting the show by making a PayPal donation or becoming a Patreon supporter. https://www.patreon.com/jamesfodor https://www.paypal.me/ScienceofEverything

Transcript

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0:00.0

Oh, wow, oh, oh, whoa, oh, wow.

0:13.0

Oh, wow.

0:15.0

Oh, James. You're listening to The Science of Everything podcast, episode 155, Embryology and Development.

0:40.8

I'm your host, James Fodor.

0:42.6

Today we're going to be talking about the process of development from starting with fertilization

0:48.2

right through to the later stages of the development of the fetus.

0:52.9

The focus is going to be on a mammalian and

0:56.1

specifically human embryonic development, although I will mention a few differences between

1:00.1

different types of animals as we go. Recommended pre-listening is episode 25, tissues, organs,

1:07.1

and systems, just for a bit of general background. And one of the reasons I'm doing this

1:12.8

episode is to provide some useful context for the next few episodes where we're going to be

1:19.4

talking about the evolution of life and the development of different types of animals,

1:24.1

and comparative development is very important for that. So I thought this episode

1:27.6

would be useful as well as a good standalone topic. One thing that I'll mention is that I'm not

1:32.7

really going to focus so much on the reproductive organs and things like the role of different

1:39.2

hormones and reproductive cycle and so forth. I'll do a separate episode on that. Here we're just

1:43.4

going to be focusing on,

1:44.4

particularly the development of the embryo. Until relatively recently, maybe the late 18th century,

1:52.7

it was thought that semen contained a premature miniature person, a miniature infant,

1:58.9

that then just becomes larger and larger during development.

2:01.9

And that was known as pre-formation.

2:04.4

A competing theory is known as epigenesis, which is the idea that an animal gradually develops

...

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