Ep74 - Vitamin D Status, Latitude and Viral Interactions - Examining the Data
The Fat Emperor Podcast
ivor cummins
4.8 • 766 Ratings
🗓️ 29 April 2020
⏱️ 16 minutes
🧾️ Download transcript
Summary
I finish this short 15 minute podcast with a scientific, philosophical question - can YOU answer it?
And yes, it's yet another one for Science and Data-Centric people everywhere
- a review of Vitamin D, #Latitude and Virus Infection severity of outcome
- fascinating stuff if I may say so
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Transcript
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| 0:00.0 | Welcome to the Fat Emperor podcast. I'm your host, Iber Cummins. Hello all. It's April 29th and I'm just bringing you another update on one aspect of the current challenge. And there's a document released at the moment relating to vitamin D with a lot of kind of recommendations based in early data. |
| 0:21.8 | So I put the link below, but it's quite interesting and it's from several |
| 0:26.9 | doctors who've put together some of the trends relating to vitamin D and perhaps |
| 0:32.1 | susceptibility to this challenge. |
| 0:34.9 | So it's showing on the screen at the moment and they go through some supporting |
| 0:38.3 | evidence for the importance of vitamin D in this whole scenario. And a couple of things they |
| 0:44.1 | highlight. One of them is that coronavirus and influenza viruses have a long history of very strong |
| 0:50.5 | seasonality, which has never fully been explained. It's been debated. And the severe |
| 0:56.9 | outbreaks for the recent issue or the current ongoing issue are heavily focused on above 20 degrees |
| 1:04.1 | latitude. So into the low kind of vitamin D availability latitudes. Vitamin D deficiency they call out occurs primarily from a lack of exposure to the sun's UV rays, particularly in summer. So during the winter when there's a lack of UV present, you get this big slump showing deficiency generally in populations so these are just |
| 1:29.3 | circumstantial though to be quite fair now the reason that this document has come out |
| 1:34.8 | and it's not fully released yet but it's kind of available is probably connected to |
| 1:40.3 | the recent studies I went through the other day on vitamin D level in humans versus severity |
| 1:47.0 | of outcome. And I'm just showing one here. There are preprint studies, but the data looks pretty |
| 1:52.0 | solid, the methodology. And they corrected for age, sex and comorbidity here, which is very |
| 1:58.0 | important. But still, as you can see, for insufficient and particularly |
| 2:02.7 | deficient in vitamin D had 10 times the rate of death for this current virus. So a 10 times |
| 2:11.2 | multiplier after some correction is pretty enormous for an associational study. So it has to be taken seriously. |
| 2:19.1 | So we'll go on and just take a few excerpts from the paper or document |
| 2:24.0 | that I've linked to below. |
| 2:27.0 | So they note that Italy, very high latitude, |
| 2:30.8 | has had the most severe outbreak and very high case fatality rate. |
... |
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