Ep149 "What makes a brain grow up resilient?" with David Sussillo
Inner Cosmos with David Eagleman
iHeartPodcasts
4.7 • 620 Ratings
🗓️ 13 April 2026
⏱️ 51 minutes
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Summary
How can a brain grow up in chaos but find its way to order? There are many ways to have a bad childhood, but why do some children break while others bend and keep going? How much of who you are is written in your genes & how much is sculpted by your environment? How many versions of you were possible & why did this one win out? Join Eagleman today with David Sussillo, who was abandoned as a child but grew up to become a neuroscientist & technologist. We’ll explore what his trajectory teaches about our genes, brains, and our own lives.
Transcript
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| 0:00.0 | How can a brain grow up in chaos and still find its way to order? There are many ways to have a bad |
| 0:11.7 | childhood, but why do some children break while others bend and keep going? How much of who you are |
| 0:18.9 | is written in your genes and how much is sculpted by your |
| 0:22.3 | environment. And if we could know everything about a child's genes and environment, would we be |
| 0:28.1 | able to predict who they would become? Why or why not? How many versions of you were possible? |
| 0:34.0 | And why did this one win out? When you look back at your childhood, which moments |
| 0:40.3 | mattered more than you realized at the time? Today we're joined by David Cicillo, who grew up in a very |
| 0:47.5 | tough childhood, abandoned by his parents when he was eight, and he had about 13 sets of surrogate parents over the years. |
| 0:55.3 | But he grew up, and he became a neuroscientist at Stanford, and then at Google Brain, |
| 1:00.2 | and now it met up. And today we're going to explore that unlikely trajectory and what it teaches |
| 1:05.9 | us about genes and brains and our own lives. |
| 1:12.7 | Welcome to Inner Cosmos with me, David Eagleman. |
| 1:15.3 | I'm a neuroscientist and author at Stanford, |
| 1:17.7 | and in these episodes, we sail deeply into our three-pound universe |
| 1:21.3 | to uncover some of the most surprising aspects of our lives. |
| 1:41.3 | Thank you. aspects of our lives. Today's episode is about the determinants of who we become. |
| 1:46.5 | When a baby human drops into the world, the brain is not yet finished. |
| 1:51.4 | As I put this in my book, LiveWired, their brain is half-baked. |
| 1:56.0 | It is still in a full-tilt construction project, where you've got billions of neurons wiring themselves |
| 2:03.0 | together, and this wiring is guided partly by genetic instructions and largely by the |
| 2:09.4 | experiences they pick up. So every moment in a baby's life is laying down traces. |
| 2:15.9 | Every interaction they have is nudging their life trajectory to go in |
... |
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